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    GIMAP2 GTPase, IMAP family member 2 [ Homo sapiens (human) ]

    Gene ID: 26157, updated on 2-Oct-2018

    Summary

    Official Symbol
    GIMAP2provided by HGNC
    Official Full Name
    GTPase, IMAP family member 2provided by HGNC
    Primary source
    HGNC:HGNC:21789
    See related
    Ensembl:ENSG00000106560 MIM:608085; Vega:OTTHUMG00000157488
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    IAN12; IMAP2; HIMAP2
    Summary
    This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
    Expression
    Broad expression in lymph node (RPKM 31.9), spleen (RPKM 29.6) and 22 other tissues See more
    Orthologs

    Genomic context

    See GIMAP2 in Genome Data Viewer
    Location:
    7q36.1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 7 NC_000007.14 (150685706..150693641)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (150382690..150390729)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene GTPase, IMAP family member 6 Neighboring gene eukaryotic translation initiation factor 2A pseudogene 3 Neighboring gene GIMAP1-GIMAP5 readthrough Neighboring gene GTPase, IMAP family member 1 Neighboring gene GTPase, IMAP family member 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included gene: GIMAP1

    Homology

    Clone Names

    • MGC24275, DKFZp586D0824

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    lipid droplet IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    GTPase IMAP family member 2
    Names
    immune-associated nucleotide-binding protein 12
    immunity associated protein 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_015660.2NP_056475.1  GTPase IMAP family member 2

      See identical proteins and their annotated locations for NP_056475.1

      Status: REVIEWED

      Source sequence(s)
      BC032345, BG687383
      Consensus CDS
      CCDS5905.1
      UniProtKB/Swiss-Prot
      Q9UG22
      UniProtKB/TrEMBL
      A0A090N8H4
      Related
      ENSP00000223293.5, OTTHUMP00000212217, ENST00000223293.9, OTTHUMT00000348948
      Conserved Domains (1) summary
      cd01852
      Location:23224
      AIG1; AvrRpt2-Induced Gene 1 (AIG1)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p12 Primary Assembly

      Range
      150685706..150693641
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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