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    PROSER2 proline and serine rich 2 [ Homo sapiens (human) ]

    Gene ID: 254427, updated on 17-Jun-2019

    Summary

    Official Symbol
    PROSER2provided by HGNC
    Official Full Name
    proline and serine rich 2provided by HGNC
    Primary source
    HGNC:HGNC:23728
    See related
    Ensembl:ENSG00000148426
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C10orf47
    Expression
    Broad expression in liver (RPKM 3.3), placenta (RPKM 2.8) and 23 other tissues See more
    Orthologs

    Genomic context

    See PROSER2 in Genome Data Viewer
    Location:
    10p14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (11823341..11872277)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (11865295..11914276)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379850 Neighboring gene uncharacterized LOC105376415 Neighboring gene PROSER2 antisense RNA 1 Neighboring gene RNA, U6 small nuclear 1095, pseudogene Neighboring gene UPF2 regulator of nonsense mediated mRNA decay Neighboring gene uncharacterized LOC105376416

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC35403

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    proline and serine-rich protein 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153256.4NP_694988.3  proline and serine-rich protein 2

      See identical proteins and their annotated locations for NP_694988.3

      Status: VALIDATED

      Source sequence(s)
      AL138898, BC048800
      Consensus CDS
      CCDS7085.1
      UniProtKB/Swiss-Prot
      Q86WR7
      Related
      ENSP00000277570.5, ENST00000277570.10
      Conserved Domains (2) summary
      PHA03247
      Location:92405
      PHA03247; large tegument protein UL36; Provisional
      pfam15385
      Location:396433
      SARG; Specifically androgen-regulated gene protein

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

      Range
      11823341..11872277
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011519438.2XP_011517740.1  proline and serine-rich protein 2 isoform X1

      See identical proteins and their annotated locations for XP_011517740.1

      UniProtKB/Swiss-Prot
      Q86WR7
      Conserved Domains (2) summary
      PHA03247
      Location:92405
      PHA03247; large tegument protein UL36; Provisional
      pfam15385
      Location:396433
      SARG; Specifically androgen-regulated gene protein
    2. XM_017016028.2XP_016871517.1  proline and serine-rich protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q86WR7
      Conserved Domains (2) summary
      PHA03247
      Location:92405
      PHA03247; large tegument protein UL36; Provisional
      pfam15385
      Location:396433
      SARG; Specifically androgen-regulated gene protein
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