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    Ambn ameloblastin [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25376, updated on 18-Apr-2019

    Summary

    Official Symbol
    Ambnprovided by RGD
    Official Full Name
    ameloblastinprovided by RGD
    Primary source
    RGD:2101
    See related
    Ensembl:ENSRNOG00000003718
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    may act as a structural component of tooth enamel matrix [RGD, Feb 2006]
    Expression
    Biased expression in Spleen (RPKM 12.7), Testes (RPKM 4.0) and 1 other tissue See more
    Orthologs

    Genomic context

    See Ambn in Genome Data Viewer
    Location:
    14p22
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (21239887..21252534, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 14 NC_005113.3 (21151232..21164256, complement)

    Chromosome 14 - NC_005113.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102554948 Neighboring gene joining chain of multimeric IgA and IgM Neighboring gene enamelin Neighboring gene amelotin Neighboring gene opiorphin prepropeptide

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    General gene information

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    growth factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    growth factor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    structural constituent of tooth enamel TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    biomineral tissue development IEA
    Inferred from Electronic Annotation
    more info
     
    cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell adhesion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    odontogenesis of dentin-containing tooth IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012900.1NP_037032.1  ameloblastin precursor

      See identical proteins and their annotated locations for NP_037032.1

      Status: PROVISIONAL

      Source sequence(s)
      U35097
      UniProtKB/Swiss-Prot
      Q62840
      Related
      ENSRNOP00000005003.6, ENSRNOT00000005003.6
      Conserved Domains (1) summary
      pfam05111
      Location:5422
      Amelin; Ameloblastin precursor (Amelin)

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005113.4 Reference Rnor_6.0 Primary Assembly

      Range
      21239887..21252534 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000082.1 Alternate Rn_Celera

      Range
      18940192..18974478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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