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    Akap9 A-kinase anchoring protein 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 246150, updated on 2-Oct-2018

    Summary

    Official Symbol
    Akap9provided by RGD
    Official Full Name
    A-kinase anchoring protein 9provided by RGD
    Primary source
    RGD:620833
    See related
    Ensembl:ENSRNOG00000026319
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Gisp; CG-NAP; Yotiao
    Expression
    Biased expression in Muscle (RPKM 257.0), Heart (RPKM 188.8) and 9 other tissues See more
    Orthologs

    Genomic context

    See Akap9 in Genome Data Viewer
    Location:
    4q13
    Exon count:
    51
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (27195346..27331582, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (27098572..27234808, complement)

    Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350665 Neighboring gene cytochrome P450, family 51 Neighboring gene uncharacterized LOC108350666 Neighboring gene mitochondrial transcription termination factor 1 Neighboring gene leucine-rich repeats and death domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    ion channel binding IEA
    Inferred from Electronic Annotation
    more info
     
    ion channel binding ISO
    Inferred from Sequence Orthology
    more info
     
    potassium channel regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    potassium channel regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase A regulatory subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein kinase A regulatory subunit binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase A regulatory subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex scaffold activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein-containing complex scaffold activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    Sertoli cell development ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to cAMP IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to cAMP ISO
    Inferred from Sequence Orthology
    more info
     
    maintenance of centrosome location IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    maintenance of centrosome location ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule nucleation IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule nucleation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of adenylate cyclase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of microtubule polymerization IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of microtubule polymerization ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of potassium ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of potassium ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cardiac muscle cell action potential involved in regulation of contraction IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cardiac muscle cell action potential involved in regulation of contraction ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of heart rate by cardiac conduction IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of heart rate by cardiac conduction ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of membrane repolarization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of postsynaptic neurotransmitter receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of postsynaptic neurotransmitter receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of ventricular cardiac muscle cell membrane repolarization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of ventricular cardiac muscle cell membrane repolarization ISO
    Inferred from Sequence Orthology
    more info
     
    response to electrical stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    Golgi stack IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Golgi stack ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    cis-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cis-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic branch IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extrinsic component of postsynaptic density membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pericentriolar material ISO
    Inferred from Sequence Orthology
    more info
     
    synaptic membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    synaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    voltage-gated potassium channel complex IEA
    Inferred from Electronic Annotation
    more info
     
    voltage-gated potassium channel complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    A-kinase anchor protein 9
    Names
    A kinase (PRKA) anchor protein (yotiao) 9
    A kinase (PRKA) anchor protein 9
    GABA-B receptor-interacting scaffolding protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037093.2NP_001032170.2  A-kinase anchor protein 9

      Status: VALIDATED

      Source sequence(s)
      AABR07059619, AABR07059620
      UniProtKB/TrEMBL
      F1LPB4
      Related
      ENSRNOP00000010118.5, ENSRNOT00000010118.6
      Conserved Domains (2) summary
      TIGR02168
      Location:131860
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam10495
      Location:35693650
      PACT_coil_coil; Pericentrin-AKAP-450 domain of centrosomal targeting protein

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

      Range
      27195346..27331582 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006236025.2XP_006236087.1  A-kinase anchor protein 9 isoform X7

      Conserved Domains (2) summary
      TIGR02168
      Location:131860
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam10495
      Location:36143695
      PACT_coil_coil; Pericentrin-AKAP-450 domain of centrosomal targeting protein
    2. XM_017592446.1XP_017447935.1  A-kinase anchor protein 9 isoform X3

    3. XM_017592447.1XP_017447936.1  A-kinase anchor protein 9 isoform X4

      UniProtKB/TrEMBL
      A0A0G2K548
      Related
      ENSRNOP00000073290.1, ENSRNOT00000090751.1
    4. XM_017592448.1XP_017447937.1  A-kinase anchor protein 9 isoform X6

    5. XM_008762686.2XP_008760908.1  A-kinase anchor protein 9 isoform X2

      Conserved Domains (2) summary
      TIGR02168
      Location:149878
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam10495
      Location:36573738
      PACT_coil_coil; Pericentrin-AKAP-450 domain of centrosomal targeting protein
    6. XM_008762685.2XP_008760907.1  A-kinase anchor protein 9 isoform X1

      Conserved Domains (2) summary
      TIGR02168
      Location:149878
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam10495
      Location:36703751
      PACT_coil_coil; Pericentrin-AKAP-450 domain of centrosomal targeting protein
    7. XM_006236023.3XP_006236085.1  A-kinase anchor protein 9 isoform X5

      See identical proteins and their annotated locations for XP_006236085.1

      Conserved Domains (2) summary
      TIGR02168
      Location:149878
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam10495
      Location:36323713
      PACT_coil_coil; Pericentrin-AKAP-450 domain of centrosomal targeting protein

    Alternate Rn_Celera

    Genomic

    1. AC_000072.1 Alternate Rn_Celera

      Range
      25482592..25617928 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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