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    invs inversin [ Danio rerio (zebrafish) ]

    Gene ID: 245946, updated on 1-Aug-2018

    Summary

    Official Symbol
    invsprovided by ZNC
    Official Full Name
    inversinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-020507-2
    See related
    Ensembl:ENSDARG00000002213 Vega:OTTDARG00000020912
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    wu:fe47e11
    Orthologs

    Genomic context

    See invs in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (27442460..27502702)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (27507923..27568341)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene syntaxin 17 Neighboring gene endoplasmic reticulum protein 44 Neighboring gene testis expressed 10 Neighboring gene si:ch211-197h24.6

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Wnt signaling pathway, organism-specific biosystem (from KEGG)
      Wnt signaling pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
    • Wnt signaling pathway, conserved biosystem (from KEGG)
      Wnt signaling pathway, conserved biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    body morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cloaca development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    convergent extension involved in gastrulation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    establishment of planar polarity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    heart looping IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    kidney development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    opsin transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    opsin transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    pronephros formation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    pronephros morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152970.1NP_694502.1  inversin

      See identical proteins and their annotated locations for NP_694502.1

      Status: PROVISIONAL

      Source sequence(s)
      AF465261
      UniProtKB/Swiss-Prot
      Q8UVC1
      Related
      ENSDARP00000014904.8, OTTDARP00000021636, ENSDART00000015688.10, OTTDART00000026361
      Conserved Domains (4) summary
      cd00204
      Location:377502
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:420509
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:482537
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:415446
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      27442460..27502702
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005158039.4XP_005158096.1  inversin isoform X1

      UniProtKB/TrEMBL
      A0A0R4IDU9
      Conserved Domains (5) summary
      cd00204
      Location:378503
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12446
      Location:722836
      DUF3682; Protein of unknown function (DUF3682)
      pfam12796
      Location:421510
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:483538
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:416447
      ANK; ANK repeat [structural motif]
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