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    Lalba lactalbumin, alpha [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24528, updated on 2-Oct-2018

    Summary

    Official Symbol
    Lalbaprovided by RGD
    Official Full Name
    lactalbumin, alphaprovided by RGD
    Primary source
    RGD:2987
    See related
    Ensembl:ENSRNOG00000010811
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    regulatory subunit of lactose synthase found in milk; involved in altering substrate specificity of galactosyltransferase [RGD, Feb 2006]
    Expression
    Biased expression in Muscle (RPKM 5.1), Testes (RPKM 4.0) and 1 other tissue See more
    Orthologs

    Genomic context

    See Lalba in Genome Data Viewer
    Location:
    7q36
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (140088420..140096347, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (139231203..139233459, complement)

    Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene olfactory receptor pseudogene 1109 Neighboring gene olfactory receptor pseudogene 1110 Neighboring gene olfactory receptor 1111 Neighboring gene uncharacterized LOC103692975 Neighboring gene KAT8 regulatory NSL complex subunit 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    lactose synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    defense response to Gram-negative bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    defense response to Gram-positive bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    lactose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    alpha-lactalbumin
    Names
    lactose synthase B protein
    NP_036726.1
    XP_017450147.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012594.1NP_036726.1  alpha-lactalbumin precursor

      See identical proteins and their annotated locations for NP_036726.1

      Status: PROVISIONAL

      Source sequence(s)
      X00461
      UniProtKB/Swiss-Prot
      P00714
      Related
      ENSRNOP00000014457.1, ENSRNOT00000014456.3
      Conserved Domains (1) summary
      pfam00062
      Location:20137
      Lys; C-type lysozyme/alpha-lactalbumin family

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

      Range
      140088420..140096347 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017594658.1XP_017450147.1  alpha-lactalbumin isoform X1

      UniProtKB/TrEMBL
      F1M7M1
      Conserved Domains (1) summary
      pfam00062
      Location:20137
      Lys; C-type lysozyme/alpha-lactalbumin family

    Alternate Rn_Celera

    Genomic

    1. AC_000075.1 Alternate Rn_Celera

      Range
      126117233..126119018 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. NW_001091349.1 Alternate Rn_Celera

      Range
      2488..2621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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