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    Fbxo21 F-box protein 21 [ Mus musculus (house mouse) ]

    Gene ID: 231670, updated on 5-Aug-2018

    Summary

    Official Symbol
    Fbxo21provided by MGI
    Official Full Name
    F-box protein 21provided by MGI
    Primary source
    MGI:MGI:1924223
    See related
    Ensembl:ENSMUSG00000032898 Vega:OTTMUSG00000056149
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AU016673; 2810425J22Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 54.7), whole brain E14.5 (RPKM 49.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Fbxo21 in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (117976550..118010191)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (118426779..118460200)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene nitric oxide synthase 1, neuronal Neighboring gene predicted gene, 30360 Neighboring gene predicted gene, 26995 Neighboring gene tescalcin Neighboring gene predicted gene, 30466 Neighboring gene F-box and WD-40 domain protein 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0875, MGC28066

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001346588.1NP_001333517.1  F-box only protein 21 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal in-frame segment and is shorter, compared to isoform 1.
      Source sequence(s)
      AK048131, AK049723, BE954194, BP754360, BY478760
      Consensus CDS
      CCDS84947.1
      UniProtKB/Swiss-Prot
      Q8VDH1
    2. NM_145564.4NP_663539.1  F-box only protein 21 isoform 1

      See identical proteins and their annotated locations for NP_663539.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK049723, BP754360
      Consensus CDS
      CCDS19607.1
      UniProtKB/Swiss-Prot
      Q8VDH1
      Related
      ENSMUSP00000143873.1, OTTMUSP00000072943, ENSMUST00000202447.3, OTTMUST00000138836
      Conserved Domains (3) summary
      TIGR02097
      Location:500597
      yccV; hemimethylated DNA binding domain
      pfam12937
      Location:3078
      F-box-like; F-box-like
      pfam13369
      Location:258388
      Transglut_core2; Transglutaminase-like superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      117976550..118010191
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530297.2XP_006530360.1  F-box only protein 21 isoform X1

      Related
      ENSMUSP00000035506.7, OTTMUSP00000072944, ENSMUST00000035579.9, OTTMUST00000138837
      Conserved Domains (3) summary
      TIGR02097
      Location:493590
      yccV; hemimethylated DNA binding domain
      pfam12937
      Location:3078
      F-box-like; F-box-like
      pfam13369
      Location:258388
      Transglut_core2; Transglutaminase-like superfamily
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