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    Prune1 prune exopolyphosphatase [ Mus musculus (house mouse) ]

    Gene ID: 229589, updated on 9-Sep-2018

    Summary

    Official Symbol
    Prune1provided by MGI
    Official Full Name
    prune exopolyphosphataseprovided by MGI
    Primary source
    MGI:MGI:1925152
    See related
    Ensembl:ENSMUSG00000015711 Vega:OTTMUSG00000022362
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Prune; HTCD37; DRES-17; PRUNEM1; Prune-M1; C130058A12; 9230112O05Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 23.6), whole brain E14.5 (RPKM 20.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Prune1 in Genome Data Viewer
    Location:
    3; 3 F2.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (95253674..95282076, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (95057596..95085998, complement)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene 128 Neighboring gene BCL2/adenovirus E1B 19kD interacting protein like Neighboring gene MINDY lysine 48 deubiquitinase 1 Neighboring gene annexin A9 Neighboring gene ceramide synthase 2 Neighboring gene SET domain, bifurcated 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Transgenic (1) 
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    exopolyphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    inorganic diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    pyrophosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    tubulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    polyphosphate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of microtubule polymerization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of neurogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    exopolyphosphatase PRUNE1
    Names
    protein prune homolog
    prune homolog
    NP_775482.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173347.2NP_775482.1  exopolyphosphatase PRUNE1

      See identical proteins and their annotated locations for NP_775482.1

      Status: PROVISIONAL

      Source sequence(s)
      BC057546
      Consensus CDS
      CCDS17610.1
      UniProtKB/Swiss-Prot
      Q8BIW1
      Related
      ENSMUSP00000015855.7, OTTMUSP00000025382, ENSMUST00000015855.7, OTTMUST00000053379
      Conserved Domains (2) summary
      COG1227
      Location:21286
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam02833
      Location:218357
      DHHA2; DHHA2 domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      95253674..95282076 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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