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    Nup153 nucleoporin 153 [ Mus musculus (house mouse) ]

    Gene ID: 218210, updated on 12-Aug-2018

    Summary

    Official Symbol
    Nup153provided by MGI
    Official Full Name
    nucleoporin 153provided by MGI
    Primary source
    MGI:MGI:2385621
    See related
    Ensembl:ENSMUSG00000021374 Vega:OTTMUSG00000043310
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C88147; B130015D15Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 42.1), thymus adult (RPKM 15.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Nup153 in Genome Data Viewer
    Location:
    13; 13 A5
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (46679902..46727849, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (46775271..46823218, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene CAP, adenylate cyclase-associated protein, 2 (yeast) Neighboring gene family with sequence similarity 8, member A1 Neighboring gene predicted gene, 46412 Neighboring gene kinesin family member 13A Neighboring gene coronin, actin binding protein 1C pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Ran GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear localization sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear localization sequence binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein membrane anchor ISO
    Inferred from Sequence Orthology
    more info
     
    structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    structural constituent of nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of RNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear pore complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    annulate lamellae ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear inclusion body ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear periphery ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear pore central transport channel IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear pore nuclear basket IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear pore nuclear basket ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasmic side of nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    nuclear pore complex protein Nup153

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175749.2NP_786925.2  nuclear pore complex protein Nup153

      Status: VALIDATED

      Source sequence(s)
      AK031006, AK044947, AK086847, BM950067, CA326562, CF897724, CF898039, CK638380
      Consensus CDS
      CCDS26486.1
      UniProtKB/TrEMBL
      E9Q3G8, Q3V3W1, Q8BRF6
      Related
      ENSMUSP00000021803.8, OTTMUSP00000063508, ENSMUST00000021803.9, OTTMUST00000113630
      Conserved Domains (4) summary
      sd00025
      Location:658677
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:718746
      zf-RanBP; Zn-finger in Ran binding protein and others
      pfam08604
      Location:114625
      Nup153; Nucleoporin Nup153-like
      pfam10599
      Location:13721462
      Nup_retrotrp_bd; Retro-transposon transporting motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      46679902..46727849 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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