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    Pla2g4b phospholipase A2, group IVB (cytosolic) [ Mus musculus (house mouse) ]

    Gene ID: 211429, updated on 12-Aug-2019

    Summary

    Official Symbol
    Pla2g4bprovided by MGI
    Official Full Name
    phospholipase A2, group IVB (cytosolic)provided by MGI
    Primary source
    MGI:MGI:2384819
    See related
    Ensembl:ENSMUSG00000098488
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1013; cPLA2-beta; A030011C02Rik
    Expression
    Broad expression in whole brain E14.5 (RPKM 10.6), CNS E14 (RPKM 10.4) and 27 other tissues See more
    Orthologs

    Genomic context

    See Pla2g4b in Genome Data Viewer
    Location:
    2; 2 E5
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    108 current GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (120033433..120043033)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (119859169..119868769)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase binding protein 1 Neighboring gene microRNA 7665 Neighboring gene predicted gene, 28042 Neighboring gene jumonji domain containing 7 Neighboring gene spectrin beta, non-erythrocytic 5 Neighboring gene predicted gene, 52559 Neighboring gene EH-domain containing 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Readthrough Gm28042

    Readthrough gene: Gm28042, Included gene: Jmjd7

    Homology

    Clone Names

    • MGC28892

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium-dependent phospholipase A2 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium-dependent phospholipase A2 activity ISO
    Inferred from Sequence Orthology
    more info
     
    calcium-dependent phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    lysophospholipase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phospholipase A2 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phospholipase A2 activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    glycerophospholipid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    glycerophospholipid catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cytosolic phospholipase A2 beta
    Names
    phospholipase A2 group IVB
    NP_663353.3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145378.4NP_663353.3  cytosolic phospholipase A2 beta

      See identical proteins and their annotated locations for NP_663353.3

      Status: VALIDATED

      Source sequence(s)
      AK137721, AL833774, DQ888308
      Consensus CDS
      CCDS38209.2
      UniProtKB/TrEMBL
      B7ZCM8, Q06G06
      Related
      ENSMUSP00000118458.1, ENSMUST00000126150.1
      Conserved Domains (2) summary
      cd04036
      Location:19137
      C2_cPLA2; C2 domain present in cytosolic PhosphoLipase A2 (cPLA2)
      cl11396
      Location:250779
      Patatin_and_cPLA2; Patatins and Phospholipases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p6 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p6 C57BL/6J

      Range
      120033433..120043033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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