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    Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 [ Mus musculus (house mouse) ]

    Gene ID: 20501, updated on 14-May-2019

    Summary

    Official Symbol
    Slc16a1provided by MGI
    Official Full Name
    solute carrier family 16 (monocarboxylic acid transporters), member 1provided by MGI
    Primary source
    MGI:MGI:106013
    See related
    Ensembl:ENSMUSG00000032902
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mct1; AL022710
    Expression
    Ubiquitous expression in colon adult (RPKM 55.3), placenta adult (RPKM 47.0) and 27 other tissues See more
    Orthologs

    Genomic context

    See Slc16a1 in Genome Data Viewer
    Location:
    3; 3 F2.2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (104638664..104658462)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (104442591..104462385)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene leucine-rich repeats and immunoglobulin-like domains 2 Neighboring gene predicted gene, 34490 Neighboring gene predicted gene, 34548 Neighboring gene predicted gene 6485

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    lactate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    monocarboxylic acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    organic cyclic compound binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    behavioral response to nutrient IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to organic cyclic compound ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome cycle ISO
    Inferred from Sequence Orthology
    more info
     
    glucose homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lactate transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    lipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    monocarboxylic acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane lactate transport ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of insulin secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to food IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion HDA PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    monocarboxylate transporter 1
    Names
    solute carrier family 16 member 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009196.4NP_033222.1  monocarboxylate transporter 1

      See identical proteins and their annotated locations for NP_033222.1

      Status: VALIDATED

      Source sequence(s)
      AK033516, BY729217
      Consensus CDS
      CCDS17702.1
      UniProtKB/Swiss-Prot
      P53986
      UniProtKB/TrEMBL
      Q544N9
      Related
      ENSMUSP00000045216.1, ENSMUST00000046212.1
      Conserved Domains (2) summary
      cd06174
      Location:20432
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00892
      Location:1466
      2A0113; monocarboxylate transporter 1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      104638664..104658462
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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