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    Ccl1 chemokine (C-C motif) ligand 1 [ Mus musculus (house mouse) ]

    Gene ID: 20290, updated on 18-Sep-2018

    Summary

    Official Symbol
    Ccl1provided by MGI
    Official Full Name
    chemokine (C-C motif) ligand 1provided by MGI
    Primary source
    MGI:MGI:98258
    See related
    Ensembl:ENSMUSG00000020702 Vega:OTTMUSG00000000926
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P500; Tca3; I-309; Scya1; Tca-3; BF534335
    Expression
    Low expression observed in reference dataset See more
    Orthologs

    Genomic context

    See Ccl1 in Genome Data Viewer
    Location:
    11 C; 11 49.99 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (82176666..82179812, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (81990168..81993314, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene chemokine (C-C motif) ligand 12 Neighboring gene chemokine (C-C motif) ligand 8 Neighboring gene predicted gene, 38577 Neighboring gene transmembrane protein 132E

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    CCR chemokine receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chemokine activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chemokine activity ISO
    Inferred from Sequence Orthology
    more info
     
    cytokine activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to interferon-gamma IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to interleukin-1 IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to tumor necrosis factor IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chemokine-mediated signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chemotaxis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    eosinophil chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    immune response IEA
    Inferred from Electronic Annotation
    more info
     
    inflammatory response IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    lymphocyte chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    monocyte chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neutrophil chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of ERK1 and ERK2 cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of inflammatory response ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of interleukin-17 secretion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of monocyte chemotaxis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    C-C motif chemokine 1
    Names
    CCR8 ligand
    SIS-epsilon
    T-cell activation protein 3
    small-inducible cytokine A1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011329.3NP_035459.1  C-C motif chemokine 1 precursor

      See identical proteins and their annotated locations for NP_035459.1

      Status: VALIDATED

      Source sequence(s)
      M17957
      Consensus CDS
      CCDS36249.1
      UniProtKB/Swiss-Prot
      P10146
      UniProtKB/TrEMBL
      Q0VB35
      Related
      ENSMUSP00000103824.2, OTTMUSP00000000867, ENSMUST00000108189.8, OTTMUST00000001804
      Conserved Domains (1) summary
      smart00199
      Location:3088
      SCY; Intercrine alpha family (small cytokine C-X-C) (chemokine CXC)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      82176666..82179812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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