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    Purb purine rich element binding protein B [ Mus musculus (house mouse) ]

    Gene ID: 19291, updated on 2-Oct-2018

    Summary

    Official Symbol
    Purbprovided by MGI
    Official Full Name
    purine rich element binding protein Bprovided by MGI
    Primary source
    MGI:MGI:1338779
    See related
    Ensembl:ENSMUSG00000094483 Vega:OTTMUSG00000005110
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cager-2; AA114818; D11Bwg0414e; 2310015K15Rik
    Orthologs

    Genomic context

    See Purb in Genome Data Viewer
    Location:
    11 A1; 11 4.16 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (6467599..6476076, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (6374776..6375920, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene small ubiquitin-related modifier 2 pseudogene Neighboring gene 40S ribosomal protein S15a pseudogene Neighboring gene myosin IG Neighboring gene small nucleolar RNA host gene 15

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA polymerase II regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase II regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    SMAD binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    purine-rich negative regulatory element binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    purine-rich negative regulatory element binding ISO
    Inferred from Sequence Orthology
    more info
     
    sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    single-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    translation repressor activity, mRNA regulatory element binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    apoptotic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    cell differentiation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    cell proliferation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    DNA replication factor A complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transcriptional activator protein Pur-beta
    Names
    PurB beta
    purine-rich single-stranded DNA-binding protein beta
    vascular actin single-stranded DNA-binding factor 2 p44 component

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011221.3NP_035351.1  transcriptional activator protein Pur-beta

      See identical proteins and their annotated locations for NP_035351.1

      Status: VALIDATED

      Source sequence(s)
      AL646020
      Consensus CDS
      CCDS24420.1
      UniProtKB/Swiss-Prot
      O35295
      Related
      ENSMUSP00000136957.1, OTTMUSP00000005331, ENSMUST00000179343.2, OTTMUST00000011438
      Conserved Domains (2) summary
      smart00712
      Location:45107
      PUR; DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria
      pfam04845
      Location:43291
      PurA; PurA ssDNA and RNA-binding protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      6467599..6476076 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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