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    Gabrr3 gamma-aminobutyric acid type A receptor rho3 subunit [ Rattus norvegicus (Norway rat) ]

    Gene ID: 192258, updated on 2-Oct-2018

    Summary

    Official Symbol
    Gabrr3provided by RGD
    Official Full Name
    gamma-aminobutyric acid type A receptor rho3 subunitprovided by RGD
    Primary source
    RGD:621564
    See related
    Ensembl:ENSRNOG00000001679
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    putative member of GABA receptor rho-subunit class [RGD, Feb 2006]
    Expression
    Biased expression in Adrenal (RPKM 5.8), Thymus (RPKM 4.7) and 9 other tissues See more
    Orthologs

    Genomic context

    See Gabrr3 in Genome Data Viewer
    Location:
    11q12
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (43046987..43099754, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 11 NC_005110.3 (46236525..46289103, complement)

    Chromosome 11 - NC_005110.4Genomic Context describing neighboring genes Neighboring gene crystallin beta-gamma domain containing 3 Neighboring gene ribosomal oxygenase 2 Neighboring gene similar to NACHT, leucine rich repeat and PYD containing 4A Neighboring gene uncharacterized LOC108352321 Neighboring gene olfactory receptor 1528 Neighboring gene olfactory receptor 1529

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    contributes_to GABA-A receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chloride channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to extracellular ligand-gated ion channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein domain specific binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nervous system process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of membrane potential IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    GABA-A receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    chloride channel complex IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    gamma-aminobutyric acid receptor subunit rho-3
    Names
    GABA receptor rho-3 subunit
    GABA(A) receptor subunit rho-3
    GABA(C) receptor
    gamma-aminobutyric acid (GABA) A receptor, rho 3
    gamma-aminobutyric acid (GABA) receptor, rho 3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_138897.1NP_620252.1  gamma-aminobutyric acid receptor subunit rho-3 precursor

      See identical proteins and their annotated locations for NP_620252.1

      Status: PROVISIONAL

      Source sequence(s)
      D50671
      UniProtKB/Swiss-Prot
      P50573
      Related
      ENSRNOP00000002281.4, ENSRNOT00000002281.4
      Conserved Domains (3) summary
      TIGR00860
      Location:58463
      LIC; Cation transporter family protein
      pfam02931
      Location:59264
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:271460
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005110.4 Reference Rnor_6.0 Primary Assembly

      Range
      43046987..43099754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017597868.1XP_017453357.1  gamma-aminobutyric acid receptor subunit rho-3 isoform X1

    Alternate Rn_Celera

    Genomic

    1. AC_000079.1 Alternate Rn_Celera

      Range
      40744702..40797196 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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