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    Cdk18 cyclin-dependent kinase 18 [ Mus musculus (house mouse) ]

    Gene ID: 18557, updated on 9-Sep-2018

    Summary

    Official Symbol
    Cdk18provided by MGI
    Official Full Name
    cyclin-dependent kinase 18provided by MGI
    Primary source
    MGI:MGI:97518
    See related
    Ensembl:ENSMUSG00000026437 Vega:OTTMUSG00000049382
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ctk18; Pctk3; AA682070
    Expression
    Broad expression in duodenum adult (RPKM 63.9), small intestine adult (RPKM 44.7) and 15 other tissues See more
    Orthologs

    Genomic context

    See Cdk18 in Genome Data Viewer
    Location:
    1; 1 E4
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (132113547..132139957, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (134010124..134036262, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4833413N01 gene Neighboring gene predicted gene, 37120 Neighboring gene predicted gene, 30153 Neighboring gene predicted gene, 30242

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    cyclin-dependent kinase 18
    Names
    PCTAIRE-motif protein kinase 3
    cell division protein kinase 18
    serine/threonine-protein kinase PCTAIRE-3
    NP_032821.1
    XP_011246242.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008795.2NP_032821.1  cyclin-dependent kinase 18

      See identical proteins and their annotated locations for NP_032821.1

      Status: VALIDATED

      Source sequence(s)
      AK004998, BQ177094, CJ070016
      Consensus CDS
      CCDS15281.1
      UniProtKB/Swiss-Prot
      Q04899
      UniProtKB/TrEMBL
      Q0VDL6
      Related
      ENSMUSP00000027697.5, OTTMUSP00000068123, ENSMUST00000027697.11, OTTMUST00000125871
      Conserved Domains (2) summary
      PLN00009
      Location:118407
      PLN00009; cyclin-dependent kinase A; Provisional
      cl21453
      Location:115402
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      132113547..132139957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247940.2XP_011246242.1  cyclin-dependent kinase 18 isoform X1

      Conserved Domains (2) summary
      PLN00009
      Location:41330
      PLN00009; cyclin-dependent kinase A; Provisional
      cl21453
      Location:38325
      PKc_like; Protein Kinases, catalytic domain

    RNA

    1. XR_387152.3 RNA Sequence

    2. XR_001783189.1 RNA Sequence

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