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    glr-1 Glutamate receptor 1 [ Caenorhabditis elegans ]

    Gene ID: 176204, updated on 2-Oct-2018

    Summary

    Gene symbol
    glr-1
    Gene description
    Glutamate receptor 1
    Primary source
    WormBase:WBGene00001612
    Locus tag
    CELE_C06E1.4
    Gene type
    protein coding
    RNA name
    Glutamate receptor 1
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

    Genomic context

    See glr-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    14
    Sequence:
    Chromosome: III; NC_003281.10 (8584256..8588615, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Dual oxidase maturation factor 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Fungus-induced protein 3

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    AMPA glutamate receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    AMPA glutamate receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    extracellularly glutamate-gated ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    ionotropic glutamate receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ionotropic glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    adult locomotory behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    associative learning IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    excitatory postsynaptic potential IEA
    Inferred from Electronic Annotation
    more info
     
    feeding behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    forward locomotion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    habituation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hyperosmotic response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    ionotropic glutamate receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    positive regulation of backward locomotion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of forward locomotion IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of backward locomotion IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of backward locomotion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to inorganic substance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to mechanical stimulus IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    response to mechanical stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sensory perception of bitter taste IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    short-term memory IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    synaptic transmission, glutamatergic IDA
    Inferred from Direct Assay
    more info
    PubMed 
    thigmotaxis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    AMPA glutamate receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dendrite IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    ionotropic glutamate receptor complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ionotropic glutamate receptor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    neuron projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuron projection membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    perinuclear endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    postsynaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    recycling endosome IEA
    Inferred from Electronic Annotation
    more info
     
    synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Glutamate receptor 1
    NP_498887.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8584256..8588615 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066486.6NP_498887.2  Glutamate receptor 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498887.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34299
      Conserved Domains (4) summary
      cd06380
      Location:10439
      PBP1_iGluR_AMPA; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the AMPA receptor
      pfam00060
      Location:593867
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:44417
      ANF_receptor; Receptor family ligand binding region
      cl21456
      Location:457832
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
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