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    Csf2rb colony stimulating factor 2 receptor beta common subunit [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171081, updated on 18-Apr-2019

    Summary

    Official Symbol
    Csf2rbprovided by RGD
    Official Full Name
    colony stimulating factor 2 receptor beta common subunitprovided by RGD
    Primary source
    RGD:620189
    See related
    Ensembl:ENSRNOG00000000187
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Csf2rb1
    Summary
    transducing subunit of high-affinity receptors for interleukin-3 (IL-3), GM-CSF, and IL-5 [RGD, Feb 2006]
    Annotation information
    Annotation category: partial on reference assembly
    Expression
    Biased expression in Kidney (RPKM 294.9), Spleen (RPKM 102.4) and 4 other tissues See more
    Orthologs

    Genomic context

    See Csf2rb in Genome Data Viewer
    Location:
    7q34
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (119554383..119568248)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (119544873..119558539)

    Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene parvalbumin Neighboring gene neutrophil cytosolic factor 4 Neighboring gene testis expressed 33 Neighboring gene thiosulfate sulfurtransferase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    cytokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    response to lipopolysaccharide IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    cytokine receptor common subunit beta
    Names
    colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage)
    colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
    interleukin 3 common beta chain

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133555.1NP_598239.1  cytokine receptor common subunit beta precursor

      See identical proteins and their annotated locations for NP_598239.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ000555
      UniProtKB/TrEMBL
      Q78ZF5
      Related
      ENSRNOP00000000203.5, ENSRNOT00000000203.5
      Conserved Domains (3) summary
      smart00060
      Location:136224
      FN3; Fibronectin type 3 domain
      cd00063
      Location:344438
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl21522
      Location:248326
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

      Range
      119554383..119568248
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000075.1 Alternate Rn_Celera

      Range
      106216478..106238726
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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