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    Il1rl1 interleukin 1 receptor-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 17082, updated on 7-Oct-2018

    Summary

    Official Symbol
    Il1rl1provided by MGI
    Official Full Name
    interleukin 1 receptor-like 1provided by MGI
    Primary source
    MGI:MGI:98427
    See related
    Ensembl:ENSMUSG00000026069 Vega:OTTMUSG00000037806
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1
    Expression
    Broad expression in liver E14.5 (RPKM 1.3), liver E14 (RPKM 1.3) and 16 other tissues See more
    Orthologs

    Genomic context

    See Il1rl1 in Genome Data Viewer
    Location:
    1 B; 1 19.19 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (40404864..40465418)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (40496494..40522260)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene interleukin 1 receptor, type I Neighboring gene interleukin 1 receptor-like 2 Neighboring gene ribosomal protein 10 pseudogene Neighboring gene interleukin 18 receptor 1 Neighboring gene interleukin 18 receptor accessory protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    interleukin-1 receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    interleukin-33 binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    interleukin-33 receptor activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular matrix IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    interleukin-1 receptor-like 1
    Names
    interleukin-33 receptor alpha chain
    lymphocyte antigen 84

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025602.3NP_001020773.1  interleukin-1 receptor-like 1 isoform a precursor

      See identical proteins and their annotated locations for NP_001020773.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC167126, AC167168, AI573400
      Consensus CDS
      CCDS35548.1
      UniProtKB/Swiss-Prot
      P14719
      Related
      ENSMUSP00000095379.3, OTTMUSP00000054731, ENSMUST00000097772.9, OTTMUST00000097562
      Conserved Domains (4) summary
      cd05757
      Location:124210
      Ig2_IL1R_like; Second immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R) and similar proteins
      smart00410
      Location:27110
      IG_like; Immunoglobulin like
      pfam01582
      Location:385540
      TIR; TIR domain
      cl11960
      Location:27110
      Ig; Immunoglobulin domain
    2. NM_001294171.1NP_001281100.1  interleukin-1 receptor-like 1 isoform b precursor

      See identical proteins and their annotated locations for NP_001281100.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate 5' terminal exon, lacks several exons, and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a. Variants 2 and 3 encode the same isoform.
      Source sequence(s)
      AC167126, AK033417, BC051445, BY228016
      Consensus CDS
      CCDS56626.1
      UniProtKB/Swiss-Prot
      P14719
      UniProtKB/TrEMBL
      Q5D095
      Related
      ENSMUSP00000134351.1, OTTMUSP00000054734, ENSMUST00000174335.7, OTTMUST00000097565
      Conserved Domains (3) summary
      cd05757
      Location:124210
      Ig2_IL1R_like; Second immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R) and similar proteins
      smart00410
      Location:27110
      IG_like; Immunoglobulin like
      cl11960
      Location:27110
      Ig; Immunoglobulin domain
    3. NM_010743.3NP_034873.2  interleukin-1 receptor-like 1 isoform b precursor

      See identical proteins and their annotated locations for NP_034873.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks several exons, and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a. Variants 2 and 3 encode the same isoform.
      Source sequence(s)
      AC167126, AC167168, AK033417
      Consensus CDS
      CCDS56626.1
      UniProtKB/Swiss-Prot
      P14719
      UniProtKB/TrEMBL
      Q5D095
      Related
      ENSMUSP00000133784.1, OTTMUSP00000054735, ENSMUST00000173514.7, OTTMUST00000097566
      Conserved Domains (3) summary
      cd05757
      Location:124210
      Ig2_IL1R_like; Second immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R) and similar proteins
      smart00410
      Location:27110
      IG_like; Immunoglobulin like
      cl11960
      Location:27110
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      40404864..40465418
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006495744.2XP_006495807.1  interleukin-1 receptor-like 1 isoform X1

      See identical proteins and their annotated locations for XP_006495807.1

      UniProtKB/Swiss-Prot
      P14719
      Conserved Domains (4) summary
      cd05757
      Location:124210
      Ig2_IL1R_like; Second immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R) and similar proteins
      smart00410
      Location:27110
      IG_like; Immunoglobulin like
      pfam01582
      Location:385540
      TIR; TIR domain
      cl11960
      Location:27110
      Ig; Immunoglobulin domain
    2. XM_017319082.1XP_017174571.1  interleukin-1 receptor-like 1 isoform X1

      UniProtKB/Swiss-Prot
      P14719
      Conserved Domains (4) summary
      cd05757
      Location:124210
      Ig2_IL1R_like; Second immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R) and similar proteins
      smart00410
      Location:27110
      IG_like; Immunoglobulin like
      pfam01582
      Location:385540
      TIR; TIR domain
      cl11960
      Location:27110
      Ig; Immunoglobulin domain
    3. XM_006495741.1XP_006495804.1  interleukin-1 receptor-like 1 isoform X1

      See identical proteins and their annotated locations for XP_006495804.1

      UniProtKB/Swiss-Prot
      P14719
      Related
      ENSMUSP00000054914.7, ENSMUST00000053043.7
      Conserved Domains (4) summary
      cd05757
      Location:124210
      Ig2_IL1R_like; Second immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R) and similar proteins
      smart00410
      Location:27110
      IG_like; Immunoglobulin like
      pfam01582
      Location:385540
      TIR; TIR domain
      cl11960
      Location:27110
      Ig; Immunoglobulin domain
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