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    STKLD1 serine/threonine kinase like domain containing 1 [ Homo sapiens (human) ]

    Gene ID: 169436, updated on 5-Aug-2018

    Summary

    Official Symbol
    STKLD1provided by HGNC
    Official Full Name
    serine/threonine kinase like domain containing 1provided by HGNC
    Primary source
    HGNC:HGNC:28669
    See related
    Ensembl:ENSG00000198870 Vega:OTTHUMG00000020862
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Sk521; SgK071; C9orf96
    Expression
    Biased expression in testis (RPKM 4.5), brain (RPKM 0.4) and 2 other tissues See more
    Orthologs

    Genomic context

    See STKLD1 in Genome Data Viewer
    Location:
    9q34.2
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 9 NC_000009.12 (133376413..133406096)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (136243284..136271220)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene SURF1, cytochrome c oxidase assembly factor Neighboring gene surfeit 2 Neighboring gene surfeit 4 Neighboring gene REX4 homolog, 3'-5' exonuclease Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 13 Neighboring gene calcium channel flower domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included gene: SURF2

    Homology

    Clone Names

    • MGC43306

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    serine/threonine kinase-like domain-containing protein STKLD1
    Names
    probable inactive protein kinase-like protein SgK071
    serine/threonine kinase-like domain-containing protein 1
    sugen kinase 071

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153710.4NP_714921.4  serine/threonine kinase-like domain-containing protein STKLD1

      See identical proteins and their annotated locations for NP_714921.4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript and encodes the protein.
      Source sequence(s)
      AK131545, AL593848, BC036504
      Consensus CDS
      CCDS35169.1
      UniProtKB/Swiss-Prot
      Q8NE28
      Related
      ENSP00000361025.3, OTTHUMP00000022465, ENST00000371957.3, OTTHUMT00000054855
      Conserved Domains (1) summary
      cd00180
      Location:34292
      PKc; Catalytic domain of Protein Kinases

    RNA

    1. NR_103997.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains multiple differences in the internal exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK131545, AL593848, BC036504

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p12 Primary Assembly

      Range
      133376413..133406096
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p12 PATCHES

    Genomic

    1. NW_009646201.1 Reference GRCh38.p12 PATCHES

      Range
      202507..232190
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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