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    NOP9 NOP9 nucleolar protein [ Homo sapiens (human) ]

    Gene ID: 161424, updated on 17-Jun-2019

    Summary

    Official Symbol
    NOP9provided by HGNC
    Official Full Name
    NOP9 nucleolar proteinprovided by HGNC
    Primary source
    HGNC:HGNC:19826
    See related
    Ensembl:ENSG00000196943 MIM:618308
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C14orf21
    Expression
    Ubiquitous expression in duodenum (RPKM 25.7), liver (RPKM 25.0) and 25 other tissues See more
    Orthologs

    Genomic context

    See NOP9 in Genome Data Viewer
    Location:
    14q12
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (24299850..24309124)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (24769075..24777379)

    Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene TGM1 promoter region Neighboring gene Rab geranylgeranyltransferase subunit alpha Neighboring gene uncharacterized LOC102725044 Neighboring gene dehydrogenase/reductase 1 Neighboring gene nonconserved acetylation island sequence 81 enhancer Neighboring gene cell death inducing DFFA like effector b Neighboring gene leukotriene B4 receptor 2 Neighboring gene leukotriene B4 receptor Neighboring gene adenylate cyclase 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Phenotypes

    NHGRI GWAS Catalog

    Description
    Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment.
    NHGRI GWA Catalog

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Rev rev HIV-1 Rev interacting protein, chromosome 14 open reading frame 21, is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA2021

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    RNA binding HDA PubMed 
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    nucleolar protein 9
    Names
    NOP9 nucleolar protein homolog
    pumilio domain-containing protein C14orf21

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001286367.2NP_001273296.1  nucleolar protein 9 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses two alternate splice sites in the coding region, which results a frameshift, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1.
      Source sequence(s)
      AB095941, AL096870, BC015481, BC025332, HY061279
      Consensus CDS
      CCDS66616.1
      UniProtKB/Swiss-Prot
      Q86U38
      Related
      ENSP00000380020.3, ENST00000396802.7
    2. NM_174913.3NP_777573.1  nucleolar protein 9 isoform 1

      See identical proteins and their annotated locations for NP_777573.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AB095941, AL096870, BC015481, HY061279
      Consensus CDS
      CCDS9624.1
      UniProtKB/Swiss-Prot
      Q86U38
      Related
      ENSP00000267425.3, ENST00000267425.8
      Conserved Domains (1) summary
      cl21719
      Location:512600
      Pumilio; Pumilio-family RNA binding domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

      Range
      24299850..24309124
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011536526.2XP_011534828.1  nucleolar protein 9 isoform X2

      Conserved Domains (1) summary
      cl21719
      Location:442530
      Pumilio; Pumilio-family RNA binding domain
    2. XM_005267385.1XP_005267442.1  nucleolar protein 9 isoform X1

      Conserved Domains (1) summary
      cl21719
      Location:526614
      Pumilio; Pumilio-family RNA binding domain
    3. XM_011536527.2XP_011534829.1  nucleolar protein 9 isoform X3

    Reference GRCh38.p13 PATCHES

    Genomic

    1. NW_018654722.1 Reference GRCh38.p13 PATCHES

      Range
      600828..610102
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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