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    Gjb5 gap junction protein, beta 5 [ Mus musculus (house mouse) ]

    Gene ID: 14622, updated on 18-Sep-2018

    Summary

    Official Symbol
    Gjb5provided by MGI
    Official Full Name
    gap junction protein, beta 5provided by MGI
    Primary source
    MGI:MGI:95723
    See related
    Ensembl:ENSMUSG00000042357 Vega:OTTMUSG00000009375
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gjb-5; Cx31.1; Cnx31.1
    Expression
    Biased expression in placenta adult (RPKM 18.0), colon adult (RPKM 3.2) and 4 other tissues See more
    Orthologs

    Genomic context

    See Gjb5 in Genome Data Viewer
    Location:
    4 D2.2; 4 61.51 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (127354809..127358164, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (127032053..127035408, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 40251 Neighboring gene gap junction protein, beta 3 Neighboring gene gap junction protein, beta 4 Neighboring gene predicted gene 12947 Neighboring gene predicted gene, 40252

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • Calcium Regulation in the Cardiac Cell, organism-specific biosystem (from WikiPathways)
      Calcium Regulation in the Cardiac Cell, organism-specific biosystemCalcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins. Calcium can act in signal transduction after influx resu...

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    cell communication IEA
    Inferred from Electronic Annotation
    more info
     
    labyrinthine layer morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spongiotrophoblast differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    trophoblast giant cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    connexin complex IEA
    Inferred from Electronic Annotation
    more info
     
    gap junction IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    gap junction beta-5 protein
    Names
    connexin-31.1
    gap junction membrane channel protein beta 5

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010291.3NP_034421.1  gap junction beta-5 protein

      See identical proteins and their annotated locations for NP_034421.1

      Status: PROVISIONAL

      Source sequence(s)
      AK082917
      Consensus CDS
      CCDS18670.1
      UniProtKB/Swiss-Prot
      Q02739
      UniProtKB/TrEMBL
      Q542M8
      Related
      ENSMUSP00000045325.2, OTTMUSP00000009765, ENSMUST00000046498.2, OTTMUST00000021352
      Conserved Domains (3) summary
      smart00037
      Location:4275
      CNX; Connexin homologues
      smart01089
      Location:139206
      Connexin_CCC; Gap junction channel protein cysteine-rich domain
      pfam00029
      Location:2208
      Connexin; Connexin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      127354809..127358164 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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