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    GRPEL2 GrpE like 2, mitochondrial [ Homo sapiens (human) ]

    Gene ID: 134266, updated on 4-Mar-2018
    Official Symbol
    GRPEL2provided by HGNC
    Official Full Name
    GrpE like 2, mitochondrialprovided by HGNC
    Primary source
    See related
    Ensembl:ENSG00000164284 Vega:OTTHUMG00000130048
    Gene type
    protein coding
    RefSeq status
    Homo sapiens
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Ubiquitous expression in esophagus (RPKM 15.4), fat (RPKM 4.6) and 24 other tissues See more
    Exon count:
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 5 NC_000005.10 (149345414..149354583)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (148724364..148734146)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene actin binding LIM protein family member 3 Neighboring gene actin filament associated protein 1 like 1 Neighboring gene GRPEL2 antisense RNA 1 Neighboring gene prenylcysteine oxidase 1 like Neighboring gene uncharacterized LOC101927046 Neighboring gene interleukin 17B

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016
    • Metabolism of proteins, organism-specific biosystem (from REACTOME)
      Metabolism of proteins, organism-specific biosystemProtein metabolism comprises the pathways of translation, post-translational modification and protein folding.
    • Mitochondrial protein import, organism-specific biosystem (from REACTOME)
      Mitochondrial protein import, organism-specific biosystemA human mitochondrion contains about 1500 proteins, more than 99% of which are encoded in the nucleus, synthesized in the cytosol and imported into the mitochondrion. Proteins are targeted to four lo...
    Products Interactant Other Gene Complex Source Pubs Description



    Clone Names

    • FLJ23713, FLJ33918, DKFZp451C205

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    adenyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    chaperone binding IEA
    Inferred from Electronic Annotation
    more info
    protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    Process Evidence Code Pubs
    protein folding IEA
    Inferred from Electronic Annotation
    more info
    protein import into mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    regulation of catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    Component Evidence Code Pubs
    mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    presequence translocase-associated import motor IBA
    Inferred from Biological aspect of Ancestor
    more info
    Preferred Names
    grpE protein homolog 2, mitochondrial

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152407.3NP_689620.2  grpE protein homolog 2, mitochondrial precursor

      See identical proteins and their annotated locations for NP_689620.2

      Status: VALIDATED

      Source sequence(s)
      AC131025, AL704536, BC036678
      Consensus CDS
      ENSP00000329558.3, OTTHUMP00000160523, ENST00000329271.7, OTTHUMT00000252327
      Conserved Domains (1) summary
      GrpE; nucleotide exchange factor GrpE

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly


    1. NC_000005.10 Reference GRCh38.p7 Primary Assembly

      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1


    1. NC_018916.2 Alternate CHM1_1.1

      GenBank, FASTA, Sequence Viewer (Graphics)
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