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    Cst8 cystatin 8 (cystatin-related epididymal spermatogenic) [ Mus musculus (house mouse) ]

    Gene ID: 13012, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cst8provided by MGI
    Official Full Name
    cystatin 8 (cystatin-related epididymal spermatogenic)provided by MGI
    Primary source
    MGI:MGI:107161
    See related
    Ensembl:ENSMUSG00000027442
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cres; Cst-rs1
    Expression
    Biased expression in genital fat pad adult (RPKM 110.3) and testis adult (RPKM 50.1) See more
    Orthologs

    Genomic context

    See Cst8 in Genome Data Viewer
    Location:
    2 G3; 2 73.56 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (148798839..148805596)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (148624575..148631320)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene cystatin domain containing 1 Neighboring gene cystatin 12 Neighboring gene cystatin 13 Neighboring gene cystatin 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cysteine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    negative regulation of peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cystatin-8
    Names
    cystatin-related epididymal spermatogenic protein
    cystatin-related epididymal-specific protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009978.2NP_034108.1  cystatin-8 precursor

      See identical proteins and their annotated locations for NP_034108.1

      Status: PROVISIONAL

      Source sequence(s)
      AK018943, S49926
      Consensus CDS
      CCDS16848.1
      UniProtKB/Swiss-Prot
      P32766
      Related
      ENSMUSP00000028931.3, ENSMUST00000028931.9
      Conserved Domains (1) summary
      smart00043
      Location:38140
      CY; Cystatin-like domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      148798839..148805596
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498658.3XP_006498721.1  cystatin-8 isoform X1

      See identical proteins and their annotated locations for XP_006498721.1

      UniProtKB/Swiss-Prot
      P32766
      Conserved Domains (1) summary
      smart00043
      Location:38140
      CY; Cystatin-like domain
    2. XM_006498659.3XP_006498722.1  cystatin-8 isoform X1

      See identical proteins and their annotated locations for XP_006498722.1

      UniProtKB/Swiss-Prot
      P32766
      Conserved Domains (1) summary
      smart00043
      Location:38140
      CY; Cystatin-like domain
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