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    Supt16 suppressor of Ty 16 [ Mus musculus (house mouse) ]

    Gene ID: 114741, updated on 2-Oct-2018

    Summary

    Official Symbol
    Supt16provided by MGI
    Official Full Name
    suppressor of Ty 16provided by MGI
    Primary source
    MGI:MGI:1890948
    See related
    Ensembl:ENSMUSG00000035726
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cdc68; Spt16; Fact140; Supt16h
    Expression
    Broad expression in CNS E11.5 (RPKM 42.5), liver E14 (RPKM 20.1) and 23 other tissues See more
    Orthologs

    Genomic context

    See Supt16 in Genome Data Viewer
    Location:
    14 C2; 14 26.83 cM
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (52160419..52197239, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (52780094..52816914, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein C Neighboring gene retinitis pigmentosa GTPase regulator interacting protein 1 Neighboring gene MRT4, mRNA turnover 4, homolog pseudogene Neighboring gene chromodomain helicase DNA binding protein 8 Neighboring gene small nucleolar RNA, C/D box 8 Neighboring gene RAB2B, member RAS oncogene family Neighboring gene TOX high mobility group box family member 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    DNA replication-independent nucleosome organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of transcription elongation from RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription elongation from RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    FACT complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    FACT complex subunit SPT16
    Names
    FACT 140 kDa subunit
    FACTp140
    chromatin-specific transcription elongation factor 140 kDa subunit
    facilitates chromatin transcription complex subunit SPT16
    suppressor of Ty 16 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033618.3NP_291096.2  FACT complex subunit SPT16

      See identical proteins and their annotated locations for NP_291096.2

      Status: VALIDATED

      Source sequence(s)
      AC159323, AF323667, AI930189, AK148506, CB202003
      Consensus CDS
      CCDS27051.1
      UniProtKB/Swiss-Prot
      Q920B9
      UniProtKB/TrEMBL
      G3X956
      Related
      ENSMUSP00000042283.7, ENSMUST00000046709.8
      Conserved Domains (1) summary
      cl25953
      Location:51001
      SPT16; FACT complex subunit (SPT16/CDC68)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      52160419..52197239 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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