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    Clic1 chloride intracellular channel 1 [ Mus musculus (house mouse) ]

    Gene ID: 114584, updated on 5-Aug-2018

    Summary

    Official Symbol
    Clic1provided by MGI
    Official Full Name
    chloride intracellular channel 1provided by MGI
    Primary source
    MGI:MGI:2148924
    See related
    Ensembl:ENSMUSG00000007041 Vega:OTTMUSG00000037145
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    G6; Clcp
    Expression
    Ubiquitous expression in large intestine adult (RPKM 126.6), thymus adult (RPKM 119.9) and 27 other tissues See more
    Orthologs

    Genomic context

    See Clic1 in Genome Data Viewer
    Location:
    17 B1; 17 18.58 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (35050243..35058719)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (35187188..35195664)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene von Willebrand factor A domain containing 7 Neighboring gene suppressor APC domain containing 1 Neighboring gene mutS homolog 5 Neighboring gene dimethylarginine dimethylaminohydrolase 2 Neighboring gene megakaryocyte and platelet inhibitory receptor G6b Neighboring gene G6b opposite strand

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    chloride channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chloride channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    voltage-gated ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    chloride transport ISO
    Inferred from Sequence Orthology
    more info
     
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of osteoblast differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of mitochondrial membrane potential IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of mitochondrial membrane potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    chloride channel complex IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    chloride intracellular channel protein 1
    Names
    NCC27
    nuclear chloride ion channel 27

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033444.2NP_254279.1  chloride intracellular channel protein 1

      See identical proteins and their annotated locations for NP_254279.1

      Status: PROVISIONAL

      Source sequence(s)
      AC087117
      Consensus CDS
      CCDS28675.1
      UniProtKB/Swiss-Prot
      Q9Z1Q5
      UniProtKB/TrEMBL
      Q542F1
      Related
      ENSMUSP00000007257.9, OTTMUSP00000053383, ENSMUST00000007257.9, OTTMUST00000095672
      Conserved Domains (1) summary
      TIGR00862
      Location:6241
      O-ClC; intracellular chloride channel protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      35050243..35058719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38.p4 129X1/SvJ

    Genomic

    1. NT_039662.3 Reference GRCm38.p4 129X1/SvJ

      Range
      1299936..1308422
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38.p4 NOD/MrkTac

    Genomic

    1. NT_187027.1 Reference GRCm38.p4 NOD/MrkTac

      Range
      1368411..1376890
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38.p4 NOD/ShiLtJ

    Genomic

    1. NT_187004.1 Reference GRCm38.p4 NOD/ShiLtJ

      Range
      1368650..1377127
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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