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    mafa v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a) [ Danio rerio (zebrafish) ]

    Gene ID: 114467, updated on 2-Oct-2018

    Summary

    Official Symbol
    mafaprovided by ZNC
    Official Full Name
    v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-010605-2
    See related
    Ensembl:ENSDARG00000015890 Vega:OTTDARG00000023427
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    maf; c-Maf; Z-cmaf; fl13d12; wu:fl13d12
    Orthologs

    Genomic context

    See mafa in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (29402220..29579911)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (29423918..29435605)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene synaptotagmin IXa Neighboring gene PTPRF interacting protein, binding protein 2a (liprin beta 2) Neighboring gene uncharacterized LOC108179989 Neighboring gene C-x(9)-C motif containing 2

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Keap1-Nrf2, organism-specific biosystem (from WikiPathways)
      Keap1-Nrf2, organism-specific biosystemBased on [http://www.nature.com/nrc/journal/v3/n10/fig_tab/nrc1189_F4.html Surh, 2003, figure 4].

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II proximal promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transcription factor Maf
    Names
    proto-oncogene c-maf
    v-maf musculoaponeurotic fibrosarcoma oncogene homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131844.2NP_571919.2  transcription factor Maf

      Status: VALIDATED

      Source sequence(s)
      BC065941, EH583521
      UniProtKB/TrEMBL
      Q6NZW9
      Related
      ENSDARP00000108952.2, OTTDARP00000024859, ENSDART00000014703.7, OTTDART00000030514
      Conserved Domains (2) summary
      cd14718
      Location:234302
      bZIP_Maf_large; Basic leucine zipper (bZIP) domain of large musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
      pfam08383
      Location:86119
      Maf_N; Maf N-terminal region

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      29402220..29579911
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021467572.1XP_021323247.1  transcription factor Maf isoform X1

      Conserved Domains (2) summary
      cd14718
      Location:234302
      bZIP_Maf_large; Basic leucine zipper (bZIP) domain of large musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
      pfam08383
      Location:86119
      Maf_N; Maf N-terminal region
    2. XM_017351895.2XP_017207384.1  transcription factor Maf isoform X1

      UniProtKB/TrEMBL
      A0A286Y8Q5
      Related
      ENSDARP00000143556.1, ENSDART00000176966.2
      Conserved Domains (2) summary
      cd14718
      Location:234302
      bZIP_Maf_large; Basic leucine zipper (bZIP) domain of large musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
      pfam08383
      Location:86119
      Maf_N; Maf N-terminal region
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