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    cdh1 cadherin 1, type 1, E-cadherin (epithelial) [ Danio rerio (zebrafish) ]

    Gene ID: 114424, updated on 2-Jun-2019

    Summary

    Official Symbol
    cdh1provided by ZNC
    Official Full Name
    cadherin 1, type 1, E-cadherin (epithelial)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-010606-1
    See related
    Ensembl:ENSDARG00000102750
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    E-cadherin

    Genomic context

    See cdh1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (53096255..53117237, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (52826603..52847585, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 7 NC_007118.5 (56206925..56228079)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene B-cadherin-like Neighboring gene uncharacterized LOC110439946 Neighboring gene uncharacterized LOC108190717 Neighboring gene cadherin-1-like

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    G-protein alpha-subunit binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    cadherin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeletal protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein homodimerization activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    adherens junction maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    adherens junction organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell migration involved in gastrulation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    cell-cell adhesion IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell-cell adhesion involved in gastrulation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell-cell adhesion involved in mesendodermal cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell-cell adhesion mediated by cadherin IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell-cell junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ectoderm development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    epiboly involved in gastrulation with mouth forming second IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    epiboly involved in gastrulation with mouth forming second IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    gastrulation with mouth forming second IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    germ cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    homophilic cell adhesion via plasma membrane adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
     
    neural tube formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    catenin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    catenin complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell cortex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell-cell adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell-cell adherens junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT desmosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    microvillus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cadherin 1, type 1, E-cadherin (epithelial)
    Names
    cadherin 1, epithelial
    hab
    half baked

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131820.1NP_571895.1  cadherin 1, type 1, E-cadherin (epithelial) precursor

      See identical proteins and their annotated locations for NP_571895.1

      Status: PROVISIONAL

      Source sequence(s)
      AF364811
      UniProtKB/TrEMBL
      Q90Z37
      Related
      ENSDARP00000133971.1, ENSDART00000172179.2
      Conserved Domains (4) summary
      cd11304
      Location:252357
      Cadherin_repeat; Cadherin tandem repeat domain
      pfam01049
      Location:727860
      Cadherin_C; Cadherin cytoplasmic region
      pfam08758
      Location:29117
      Cadherin_pro; Cadherin prodomain like
      cl09101
      Location:144244
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      53096255..53117237 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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