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    Slc38a1 solute carrier family 38, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 105727, updated on 12-Aug-2019

    Summary

    Official Symbol
    Slc38a1provided by MGI
    Official Full Name
    solute carrier family 38, member 1provided by MGI
    Primary source
    MGI:MGI:2145895
    See related
    Ensembl:ENSMUSG00000023169
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NAT2; AA408026; AA409865; AL022800; AU015942
    Expression
    Broad expression in cerebellum adult (RPKM 28.9), placenta adult (RPKM 22.1) and 23 other tissues See more
    Orthologs

    Genomic context

    See Slc38a1 in Genome Data Viewer
    Location:
    15; 15 F1
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    108 current GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (96571418..96643438, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (96401849..96473344, complement)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41392 Neighboring gene predicted gene, 32406 Neighboring gene predicted gene, 32457 Neighboring gene predicted gene, 46503 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    L-glutamine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    amino acid transport IEA
    Inferred from Electronic Annotation
    more info
     
    glutamine transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    sodium-coupled neutral amino acid transporter 1
    Names
    MNat2
    N-system amino acid transporter 2
    amino acid transporter A1
    system A amino acid transporter 1
    system N amino acid transporter 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166456.1NP_001159928.1  sodium-coupled neutral amino acid transporter 1

      See identical proteins and their annotated locations for NP_001159928.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
      Source sequence(s)
      AC109201, AC123606, AK035098, AK082683
      Consensus CDS
      CCDS27777.1
      UniProtKB/Swiss-Prot
      Q8K2P7
      Related
      ENSMUSP00000085801.5, ENSMUST00000088454.12
      Conserved Domains (2) summary
      COG0814
      Location:68473
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:69472
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    2. NM_001166458.1NP_001159930.1  sodium-coupled neutral amino acid transporter 1

      See identical proteins and their annotated locations for NP_001159930.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
      Source sequence(s)
      AC123606, AK081724
      Consensus CDS
      CCDS27777.1
      UniProtKB/Swiss-Prot
      Q8K2P7
      Related
      ENSMUSP00000085799.4, ENSMUST00000088452.10
      Conserved Domains (2) summary
      COG0814
      Location:68473
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:69472
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    3. NM_134086.4NP_598847.2  sodium-coupled neutral amino acid transporter 1

      See identical proteins and their annotated locations for NP_598847.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1-3 encode the same protein.
      Source sequence(s)
      AC123606, AK034130, AK165188
      Consensus CDS
      CCDS27777.1
      UniProtKB/Swiss-Prot
      Q8K2P7
      Related
      ENSMUSP00000097833.2, ENSMUST00000100262.3
      Conserved Domains (2) summary
      COG0814
      Location:68473
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:69472
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p6 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p6 C57BL/6J

      Range
      96571418..96643438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030248259.1XP_030104119.1  sodium-coupled neutral amino acid transporter 1 isoform X1

    2. XM_030248257.1XP_030104117.1  sodium-coupled neutral amino acid transporter 1 isoform X1

    3. XM_030248258.1XP_030104118.1  sodium-coupled neutral amino acid transporter 1 isoform X1

    4. XM_006520235.4XP_006520298.1  sodium-coupled neutral amino acid transporter 1 isoform X1

      See identical proteins and their annotated locations for XP_006520298.1

      UniProtKB/Swiss-Prot
      Q8K2P7
      Conserved Domains (2) summary
      COG0814
      Location:68473
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:69472
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
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