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    SLC30A9 solute carrier family 30 member 9 [ Homo sapiens (human) ]

    Gene ID: 10463, updated on 14-Oct-2018

    Summary

    Official Symbol
    SLC30A9provided by HGNC
    Official Full Name
    solute carrier family 30 member 9provided by HGNC
    Primary source
    HGNC:HGNC:1329
    See related
    Ensembl:ENSG00000014824 MIM:604604; Vega:OTTHUMG00000099387
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HUEL; ZNT9; GAC63; C4orf1; BILAPES
    Expression
    Ubiquitous expression in kidney (RPKM 32.5), brain (RPKM 27.2) and 25 other tissues See more
    Orthologs

    Genomic context

    See SLC30A9 in Genome Data Viewer
    Location:
    4p13
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 4 NC_000004.12 (41990502..42087534)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (41992516..42089551)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374426 Neighboring gene transmembrane protein 33 Neighboring gene DDB1 and CUL4 associated factor 4 like 1 Neighboring gene ATPase Na+/K+ transporting subunit beta 1 pseudogene 1 Neighboring gene VISTA enhancer hs847 Neighboring gene BEN domain containing 4 Neighboring gene uncharacterized LOC105374428

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Zinc homeostasis, organism-specific biosystem (from WikiPathways)
      Zinc homeostasis, organism-specific biosystemZinc is a transition metal and catalytic cofactor involved in many biological processes such as proliferation, development and differentiation, regulation of DNA synthesis, genomic stability, cell ac...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA-binding transcription factor activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    DNA-binding transcription factor activity, RNA polymerase II-specific ISM
    Inferred from Sequence Model
    more info
    PubMed 
    cation transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chromatin binding IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear receptor transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear receptor transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cation transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    cellular zinc ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular zinc ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nucleotide-excision repair TAS
    Traceable Author Statement
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    zinc ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasmic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc transporter 9
    Names
    GRIP1-dependent nuclear receptor coactivator
    expressed in human embryonic lung
    human embryonic lung protein
    solute carrier family 30 (zinc transporter), member 9
    znT-9

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_006345.3NP_006336.3  zinc transporter 9

      See identical proteins and their annotated locations for NP_006336.3

      Status: VALIDATED

      Source sequence(s)
      AA427879, AY594282, BC007732, BC022981, BG323207
      Consensus CDS
      CCDS3465.1
      UniProtKB/Swiss-Prot
      Q6PML9
      UniProtKB/TrEMBL
      A0A0S2Z514
      Related
      ENSP00000264451.6, OTTHUMP00000125233, ENST00000264451.11, OTTHUMT00000216842
      Conserved Domains (3) summary
      TIGR00598
      Location:124216
      rad14; DNA repair protein
      TIGR01297
      Location:254522
      CDF; cation diffusion facilitator family transporter
      pfam01545
      Location:251450
      Cation_efflux; Cation efflux family

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p12 Primary Assembly

      Range
      41990502..42087534
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017007654.2XP_016863143.1  zinc transporter 9 isoform X1

    RNA

    1. XR_001741095.2 RNA Sequence

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