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    Maml1 mastermind like transcriptional coactivator 1 [ Mus musculus (house mouse) ]

    Gene ID: 103806, updated on 2-Oct-2018

    Summary

    Official Symbol
    Maml1provided by MGI
    Official Full Name
    mastermind like transcriptional coactivator 1provided by MGI
    Primary source
    MGI:MGI:1890504
    See related
    Ensembl:ENSMUSG00000050567 Vega:OTTMUSG00000005580
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mam1; Mam-1; AI644666; AW743257; mKIAA0200; D930008C07Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 11.2), thymus adult (RPKM 11.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Maml1 in Genome Data Viewer
    Location:
    11; 11 B1.3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (50255634..50293142, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (50069136..50105838, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene mannoside acetylglucosaminyltransferase 4, isoenzyme B Neighboring gene microRNA 6919 Neighboring gene leukotriene C4 synthase Neighboring gene calnexin Neighboring gene predicted gene, 46280

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    peptide antigen binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription coactivator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    MAML1-RBP-Jkappa- ICN1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    mastermind-like protein 1
    Names
    maml1
    mastermind like 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175334.3NP_780543.2  mastermind-like protein 1

      See identical proteins and their annotated locations for NP_780543.2

      Status: VALIDATED

      Source sequence(s)
      AI509152, AK129088, BC058658, BC094599
      Consensus CDS
      CCDS24632.2
      UniProtKB/Swiss-Prot
      Q6T264
      Related
      ENSMUSP00000059210.4, OTTMUSP00000005743, ENSMUST00000059458.4, OTTMUST00000012408
      Conserved Domains (2) summary
      pfam03153
      Location:278444
      TFIIA; Transcription factor IIA, alpha/beta subunit
      pfam09596
      Location:1471
      MamL-1; MamL-1 domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      50255634..50293142 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531918.3XP_006531981.1  mastermind-like protein 1 isoform X1

      Conserved Domains (2) summary
      pfam03153
      Location:318484
      TFIIA; Transcription factor IIA, alpha/beta subunit
      pfam09596
      Location:1471
      MamL-1; MamL-1 domain
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