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    EN2 engrailed homeobox 2 [ Gallus gallus (chicken) ]

    Gene ID: 100859435, updated on 14-Feb-2019

    Summary

    Official Symbol
    EN2provided by CGNC
    Official Full Name
    engrailed homeobox 2provided by CGNC
    Primary source
    CGNC:63707
    See related
    Ensembl:ENSGALG00000041295
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    En-2; Gg-En-2
    Orthologs

    Genomic context

    See EN2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    104 current GRCg6a (GCF_000002315.5) 2 NC_006089.5 (7961555..7963672)
    103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 2 NC_006089.4 (7907138..7927624)
    103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 2 Unlocalized Scaffold NT_458962.1 (91..417)
    102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 2 NC_006089.3 (7875412..7877529)

    Chromosome 2 - NC_006089.5Genomic Context describing neighboring genes Neighboring gene insulin induced gene 1 Neighboring gene uncharacterized LOC112531936 Neighboring gene RNA-binding protein 25-like Neighboring gene uncharacterized LOC112531937 Neighboring gene uncharacterized LOC107052613

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    axon guidance IDA
    Inferred from Direct Assay
    more info
    PubMed 
    embryonic brain development IEA
    Inferred from Electronic Annotation
    more info
     
    hindbrain development IEA
    Inferred from Electronic Annotation
    more info
     
    midbrain development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of neuron apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of neuron death IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    neuron differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of translation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    RSC-type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fibrillar center IEA
    Inferred from Electronic Annotation
    more info
     
    filopodium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    growth cone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lamellipodium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuron projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    homeobox protein engrailed-2
    Names
    engrailed protein
    homeobox protein en-2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001267719.1NP_001254648.1  homeobox protein engrailed-2

      See identical proteins and their annotated locations for NP_001254648.1

      Status: PROVISIONAL

      Source sequence(s)
      AADN05000033
      UniProtKB/Swiss-Prot
      Q05917
      Related
      ENSGALP00000045557.2, ENSGALT00000075534.2
      Conserved Domains (2) summary
      pfam00046
      Location:203256
      Homeobox; Homeobox domain
      pfam10525
      Location:258287
      Engrail_1_C_sig; Engrailed homeobox C-terminal signature domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCg6a Primary Assembly

    Genomic

    1. NC_006089.5 Reference GRCg6a Primary Assembly

      Range
      7961555..7963672
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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