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    ABCB11 ATP binding cassette subfamily B member 11 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

    Gene ID: 100590891, updated on 19-Jan-2018

    Summary

    Gene symbol
    ABCB11
    Gene description
    ATP binding cassette subfamily B member 11
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nomascus leucogenys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
    Orthologs

    Genomic context

    See ABCB11 in Genome Data Viewer
    Location:
    chromosome: 22a
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    102 current Nleu_3.0 (GCF_000146795.2) 22a NC_019837.1 (58517352..58566032, complement)

    Chromosome 22a - NC_019837.1Genomic Context describing neighboring genes Neighboring gene SPC25, NDC80 kinetochore complex component Neighboring gene glucose-6-phosphatase catalytic subunit 2 Neighboring gene dehydrogenase/reductase 9 Neighboring gene ubiquitin-conjugating enzyme E2 variant 1 pseudogene

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_019837.1 Chromosome 22a Reference Nleu_3.0

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • ABC transporters, organism-specific biosystem (from KEGG)
      ABC transporters, organism-specific biosystemThe ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of ...
    • ABC transporters, conserved biosystem (from KEGG)
      ABC transporters, conserved biosystemThe ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of ...
    • Bile secretion, organism-specific biosystem (from KEGG)
      Bile secretion, organism-specific biosystemBile is a vital secretion, essential for digestion and absorption of fats and fat-soluble vitamins in the small intestine. Moreover, bile is an important route of elimination for excess cholesterol a...
    • Bile secretion, conserved biosystem (from KEGG)
      Bile secretion, conserved biosystemBile is a vital secretion, essential for digestion and absorption of fats and fat-soluble vitamins in the small intestine. Moreover, bile is an important route of elimination for excess cholesterol a...
    • Endocrine resistance, organism-specific biosystem (from KEGG)
      Endocrine resistance, organism-specific biosystemEndocrine therapy is a key treatment strategy to control or eradicate hormone-responsive breast cancer. The most commonly used endocrine therapy agents are selective estrogen receptor modulators (SER...
    • Endocrine resistance, conserved biosystem (from KEGG)
      Endocrine resistance, conserved biosystemEndocrine therapy is a key treatment strategy to control or eradicate hormone-responsive breast cancer. The most commonly used endocrine therapy agents are selective estrogen receptor modulators (SER...

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Nleu_3.0

    Genomic

    1. NC_019837.1 Reference Nleu_3.0

      Range
      58517352..58566032 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012496010.1XP_012351464.1  bile salt export pump

      Conserved Domains (4) summary
      cd03249
      Location:554793
      ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
      COG1132
      Location:217790
      MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]
      pfam00664
      Location:236483
      ABC_membrane; ABC transporter transmembrane region
      cl21455
      Location:1133
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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