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    GCLC glutamate-cysteine ligase catalytic subunit [ Sus scrofa (pig) ]

    Gene ID: 100522018, updated on 2-Oct-2018

    Summary

    Gene symbol
    GCLC
    Gene description
    glutamate-cysteine ligase catalytic subunit
    See related
    Ensembl:ENSSSCG00000001488 Vega:OTTSUSG00000000762
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in liver (RPKM 21.7), ovary (RPKM 19.5) and 8 other tissues See more
    Orthologs

    Genomic context

    See GCLC in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 7 NC_010449.5 (27209565..27253535)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 7 NC_010449.4 (31702759..31747437)

    Chromosome 7 - NC_010449.5Genomic Context describing neighboring genes Neighboring gene kelch like family member 31 Neighboring gene uncharacterized LOC102166539 Neighboring gene uncharacterized LOC110261503 Neighboring gene uncharacterized LOC110261504

    Genomic regions, transcripts, and products

    Expression

    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Pathways from BioSystems

    General protein information

    Preferred Names
    glutamate--cysteine ligase catalytic subunit

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010449.5 Reference Sscrofa11.1 Primary Assembly

      Range
      27209565..27253535
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021098556.1XP_020954215.1  glutamate--cysteine ligase catalytic subunit isoform X3

      Related
      ENSSSCP00000001618.3, ENSSSCT00000001660.4
      Conserved Domains (1) summary
      pfam03074
      Location:183559
      GCS; Glutamate-cysteine ligase
    2. XM_021098555.1XP_020954214.1  glutamate--cysteine ligase catalytic subunit isoform X2

      Related
      ENSSSCP00000054556.1, ENSSSCT00000054822.1
      Conserved Domains (1) summary
      pfam03074
      Location:236573
      GCS; Glutamate-cysteine ligase
    3. XM_003482164.4XP_003482212.1  glutamate--cysteine ligase catalytic subunit isoform X1

      Related
      ENSSSCP00000041795.1, OTTSUSP00000008928, ENSSSCT00000054492.1
      Conserved Domains (2) summary
      PRK08059
      Location:13125
      PRK08059; general stress protein 13; Validated
      pfam03074
      Location:236612
      GCS; Glutamate-cysteine ligase
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