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    cacna1c.S calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 100462911, updated on 8-Apr-2017

    Summary

    Symbol
    cacna1c.S
    Full Name
    calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog
    Primary source
    Xenbase:XB-GENE-6492375
    Locus tag
    XELAEV_18019866mg
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    cav1.2; cacna1c; ca(v)1.2

    Genomic context

    See cacna1c.S in Genome Data Viewer
    Location:
    chromosome: 3S
    Exon count:
    48
    Annotation release Status Assembly Chr Location
    100 current Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (5371504..5566483, complement)

    Chromosome 3S - NC_030729.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein MGC68990 Neighboring gene cat eye syndrome critical region protein 6-like Neighboring gene interleukin-17 receptor A-like Neighboring gene decapping mRNA 1B S homeolog Neighboring gene leucine-rich repeats and transmembrane domains 2 S homeolog

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_030729.1 Chromosome 3S Reference Xenopus_laevis_v2 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Adrenergic signaling in cardiomyocytes, organism-specific biosystem (from KEGG)
      Adrenergic signaling in cardiomyocytes, organism-specific biosystemCardiac myocytes express at least six subtypes of adrenergic receptor (AR) which include three subtypes of beta-AR (beta-1, beta-2, beta-3) and three subtypes of the alpha-1-AR (alpha-1A, alpha-1B, a...
    • Adrenergic signaling in cardiomyocytes, conserved biosystem (from KEGG)
      Adrenergic signaling in cardiomyocytes, conserved biosystemCardiac myocytes express at least six subtypes of adrenergic receptor (AR) which include three subtypes of beta-AR (beta-1, beta-2, beta-3) and three subtypes of the alpha-1-AR (alpha-1A, alpha-1B, a...
    • Calcium signaling pathway, organism-specific biosystem (from KEGG)
      Calcium signaling pathway, organism-specific biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
    • Calcium signaling pathway, conserved biosystem (from KEGG)
      Calcium signaling pathway, conserved biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
    • Cardiac muscle contraction, organism-specific biosystem (from KEGG)
      Cardiac muscle contraction, organism-specific biosystemContraction of the heart is a complex process initiated by the electrical excitation of cardiac myocytes (excitation-contraction coupling, ECC). In cardiac myocytes, Ca2+ influx induced by activation...
    • Cardiac muscle contraction, conserved biosystem (from KEGG)
      Cardiac muscle contraction, conserved biosystemContraction of the heart is a complex process initiated by the electrical excitation of cardiac myocytes (excitation-contraction coupling, ECC). In cardiac myocytes, Ca2+ influx induced by activation...
    • GnRH signaling pathway, organism-specific biosystem (from KEGG)
      GnRH signaling pathway, organism-specific biosystemGonadotropin-releasing hormone (GnRH) secretion from the hypothalamus acts upon its receptor in the anterior pituitary to regulate the production and release of the gonadotropins, LH and FSH. The GnR...
    • GnRH signaling pathway, conserved biosystem (from KEGG)
      GnRH signaling pathway, conserved biosystemGonadotropin-releasing hormone (GnRH) secretion from the hypothalamus acts upon its receptor in the anterior pituitary to regulate the production and release of the gonadotropins, LH and FSH. The GnR...
    • MAPK signaling pathway, organism-specific biosystem (from KEGG)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, conserved biosystem (from KEGG)
      MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • Vascular smooth muscle contraction, organism-specific biosystem (from KEGG)
      Vascular smooth muscle contraction, organism-specific biosystemThe vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regula...
    • Vascular smooth muscle contraction, conserved biosystem (from KEGG)
      Vascular smooth muscle contraction, conserved biosystemThe vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regula...

    General protein information

    Preferred Names
    voltage-dependent L-type calcium channel subunit alpha-1C
    Names
    calcium channel voltage-dependent L type Cav1.2, alpha 1c subunit

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v2 Primary Assembly

    Genomic

    1. NC_030729.1 Reference Xenopus_laevis_v2 Primary Assembly

      Range
      5371504..5566483 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018254825.1XP_018110314.1  voltage-dependent L-type calcium channel subunit alpha-1C isoform X2

    2. XM_018254824.1XP_018110313.1  voltage-dependent L-type calcium channel subunit alpha-1C isoform X1

    3. XM_018254826.1XP_018110315.1  voltage-dependent L-type calcium channel subunit alpha-1C isoform X3

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