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    PTPN1 protein tyrosine phosphatase, non-receptor type 1 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100354834, updated on 3-Apr-2017

    Summary

    Gene symbol
    PTPN1
    Gene description
    protein tyrosine phosphatase, non-receptor type 1
    See related
    Ensembl:ENSOCUG00000008605
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs

    Genomic context

    See PTPN1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    102 current OryCun2.0 (GCF_000003625.3) Unplaced Scaffold NW_003159448.1 (786320..799640, complement)

    NW_003159448.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103345625 Neighboring gene RIPOR family member 3

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NW_003159448.1 Unplaced Scaffold Reference OryCun2.0 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Adherens junction, organism-specific biosystem (from KEGG)
      Adherens junction, organism-specific biosystemCell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation....
    • Adherens junction, conserved biosystem (from KEGG)
      Adherens junction, conserved biosystemCell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation....
    • Insulin resistance, organism-specific biosystem (from KEGG)
      Insulin resistance, organism-specific biosystemInsulin resistance is a condition where cells become resistant to the effects of insulin. It is often found in people with health disorders, including obesity, type 2 diabetes mellitus, non-alcoholic...
    • Insulin signaling pathway, organism-specific biosystem (from KEGG)
      Insulin signaling pathway, organism-specific biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...
    • Insulin signaling pathway, conserved biosystem (from KEGG)
      Insulin signaling pathway, conserved biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...

    General protein information

    Preferred Names
    tyrosine-protein phosphatase non-receptor type 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Oryctolagus cuniculus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference OryCun2.0 Primary Assembly

    Genomic

    1. NW_003159448.1 Reference OryCun2.0 Primary Assembly

      Range
      786320..799640 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017338641.1XP_017194130.1  tyrosine-protein phosphatase non-receptor type 1

      UniProtKB/TrEMBL
      U3KM97
      Related
      ENSOCUP00000026355.1, ENSOCUT00000033307.1
      Conserved Domains (2) summary
      cd00047
      Location:1203
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam00102
      Location:5203
      Y_phosphatase; Protein-tyrosine phosphatase
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