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    PIAS1 protein inhibitor of activated STAT 1 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100339509, updated on 14-Jun-2019

    Summary

    Gene symbol
    PIAS1
    Gene description
    protein inhibitor of activated STAT 1
    See related
    Ensembl:ENSOCUG00000000618
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs

    Genomic context

    See PIAS1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    102 current OryCun2.0 (GCF_000003625.3) 17 NC_013685.1 (4347986..4488831, complement)

    Chromosome 17 - NC_013685.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103351074 Neighboring gene CLN6 transmembrane ER protein Neighboring gene calmodulin like 4 Neighboring gene SKI family transcriptional corepressor 1 Neighboring gene mitogen-activated protein kinase kinase 5

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_013685.1 Chromosome 17 Reference OryCun2.0 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Hepatitis C, organism-specific biosystem (from KEGG)
      Hepatitis C, organism-specific biosystemHepatitis C virus (HCV) is a major cause of chronic liver disease. The HCV employ several strategies to perturb host cell immunity. After invasion, HCV RNA genome functions directly as an mRNA in the...
    • Hepatitis C, conserved biosystem (from KEGG)
      Hepatitis C, conserved biosystemHepatitis C virus (HCV) is a major cause of chronic liver disease. The HCV employ several strategies to perturb host cell immunity. After invasion, HCV RNA genome functions directly as an mRNA in the...
    • Jak-STAT signaling pathway, organism-specific biosystem (from KEGG)
      Jak-STAT signaling pathway, organism-specific biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Jak-STAT signaling pathway, conserved biosystem (from KEGG)
      Jak-STAT signaling pathway, conserved biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Ubiquitin mediated proteolysis, organism-specific biosystem (from KEGG)
      Ubiquitin mediated proteolysis, organism-specific biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
    • Ubiquitin mediated proteolysis, conserved biosystem (from KEGG)
      Ubiquitin mediated proteolysis, conserved biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...

    General protein information

    Preferred Names
    E3 SUMO-protein ligase PIAS1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Oryctolagus cuniculus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference OryCun2.0 Primary Assembly

    Genomic

    1. NC_013685.1 Reference OryCun2.0 Primary Assembly

      Range
      4347986..4488831 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008268843.2XP_008267065.1  E3 SUMO-protein ligase PIAS1

      UniProtKB/TrEMBL
      G1SDP8
      Related
      ENSOCUP00000000539.2, ENSOCUT00000000619.3
      Conserved Domains (3) summary
      smart00513
      Location:1145
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam02891
      Location:331379
      zf-MIZ; MIZ/SP-RING zinc finger
      pfam14324
      Location:135271
      PINIT; PINIT domain

    RNA

    1. XR_001794958.1 RNA Sequence

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