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    DNASE2 deoxyribonuclease 2, lysosomal [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100171654, updated on 7-Oct-2018

    Summary

    Gene symbol
    DNASE2
    Gene description
    deoxyribonuclease 2, lysosomal
    Locus tag
    CR201_G0047853
    See related
    Ensembl:ENSPPYG00000009611
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Orthologs

    Genomic context

    See DNASE2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Susie_PABv2 (GCF_002880775.1) 19 NC_036922.1 (12885861..12891939, complement)
    102 previous assembly P_pygmaeus_2.0.2 (GCF_000001545.4) 19 NC_012610.1 (13096236..13102544, complement)

    Chromosome 19 - NC_036922.1Genomic Context describing neighboring genes Neighboring gene retbindin Neighboring gene microtubule associated serine/threonine kinase 1 Neighboring gene Kruppel like factor 1 Neighboring gene 40S ribosomal protein S6-like Neighboring gene glutaryl-CoA dehydrogenase

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Lysosome, organism-specific biosystem (from KEGG)
      Lysosome, organism-specific biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
    • Lysosome, conserved biosystem (from KEGG)
      Lysosome, conserved biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...

    General protein information

    Preferred Names
    deoxyribonuclease-2-alpha
    Names
    deoxyribonuclease II, lysosomal
    NP_001124800.1
    XP_009251131.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001131328.1NP_001124800.1  deoxyribonuclease-2-alpha precursor

      See identical proteins and their annotated locations for NP_001124800.1

      Status: PROVISIONAL

      Source sequence(s)
      CR857461
      UniProtKB/TrEMBL
      Q5REQ7
      Related
      ENSPPYP00000010775, ENSPPYT00000011197
      Conserved Domains (2) summary
      pfam03265
      Location:18345
      DNase_II; Deoxyribonuclease II
      cl15239
      Location:15176
      PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

    RefSeqs of Annotated Genomes: Pongo abelii Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Susie_PABv2 Primary Assembly

    Genomic

    1. NC_036922.1 Reference Susie_PABv2 Primary Assembly

      Range
      12885861..12891939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009252856.2XP_009251131.1  deoxyribonuclease-2-alpha isoform X1

      Conserved Domains (3) summary
      cd09191
      Location:154292
      PLDc_DNaseII_alpha_2; Catalytic domain, repeat 2, of Deoxyribonuclease II alpha and similar proteins
      pfam03265
      Location:18290
      DNase_II; Deoxyribonuclease II
      cl15239
      Location:15116
      PLDc_SF; Catalytic domain of phospholipase D superfamily proteins
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