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    mitf melanocyte inducing transcription factor [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100101790, updated on 16-Oct-2018

    Summary

    Official Symbol
    mitfprovided by Xenbase
    Official Full Name
    melanocyte inducing transcription factorprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-484962
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    ws2a; mitfa; MITF-A; mitf-b
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs

    Genomic context

    See mitf in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (130940640..131096810, complement)
    102 previous assembly Xtropicalis_v7 (GCF_000004195.2) Unplaced Scaffold NW_004668236.1 (130427903..130584073, complement)

    Chromosome 4 - NC_030680.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein mgc147226 Neighboring gene 2-epi-5-epi-valiolone synthase-like Neighboring gene FERM domain containing 4B Neighboring gene leiomodin 3

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Melanogenesis, organism-specific biosystem (from KEGG)
      Melanogenesis, organism-specific biosystemCutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory cont...
    • Melanogenesis, conserved biosystem (from KEGG)
      Melanogenesis, conserved biosystemCutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory cont...
    • Mitophagy - animal, organism-specific biosystem (from KEGG)
      Mitophagy - animal, organism-specific biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...
    • Mitophagy - animal, conserved biosystem (from KEGG)
      Mitophagy - animal, conserved biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...

    General gene information

    Homology

    General protein information

    Preferred Names
    microphthalmia-associated transcription factor

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100277.1NP_001093747.1  microphthalmia-associated transcription factor

      See identical proteins and their annotated locations for NP_001093747.1

      Status: PROVISIONAL

      Source sequence(s)
      BC135968
      UniProtKB/TrEMBL
      A4IID0
      Conserved Domains (3) summary
      cd00083
      Location:269329
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam11851
      Location:357480
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:56194
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_tropicalis_v9.1 Primary Assembly

    Genomic

    1. NC_030680.1 Reference Xenopus_tropicalis_v9.1 Primary Assembly

      Range
      130940640..131096810 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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