mitf melanocyte inducing transcription factor [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: mitfprovided by Xenbase
Official Full Name: melanocyte inducing transcription factorprovided by Xenbase
Primary source: Xenbase:XB-GENE-484962
See related: Ensembl:ENSXETG00000039276
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: ws2a; mitfa; MITF-A; mitf-b
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	4	NC_030680.2 (141515894..141678634, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	4	NC_030680.1 (130940640..131096810, complement)

Chromosome 4 - NC_030680.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Revealing mitf functions and visualizing allografted tumor metastasis in colorless and immunodeficient Xenopus tropicalis.
Title: Revealing mitf functions and visualizing allografted tumor metastasis in colorless and immunodeficient Xenopus tropicalis.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: microphthalmia-associated transcription factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001100277.1 → NP_001093747.1 microphthalmia-associated transcription factor

See identical proteins and their annotated locations for NP_001093747.1

Status: PROVISIONAL

Source sequence(s)

BC135968

UniProtKB/TrEMBL

A0A6I8S8P5, A4IID0

Related

ENSXETP00000089559.2, ENSXETT00000086972.2

Conserved Domains (3) summary

cd00083
Location:269 → 329

HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

pfam11851
Location:357 → 480

DUF3371; Domain of unknown function (DUF3371)

pfam15951
Location:56 → 194

MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus