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    MSH3 mutS homolog 3 [ Equus caballus (horse) ]

    Gene ID: 100073255, updated on 26-Sep-2018

    Summary

    Official Symbol
    MSH3provided by VGNC
    Official Full Name
    mutS homolog 3provided by VGNC
    Primary source
    VGNC:VGNC:20386
    See related
    Ensembl:ENSECAG00000009962
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs

    Genomic context

    See MSH3 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 14 NC_009157.3 (85447176..85602857, complement)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 14 NC_009157.2 (85012546..85170294, complement)

    Chromosome 14 - NC_009157.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111767901 Neighboring gene creatine kinase, mitochondrial 2 Neighboring gene Ras protein specific guanine nucleotide releasing factor 2 Neighboring gene dihydrofolate reductase Neighboring gene ankyrin repeat domain 34B Neighboring gene family with sequence similarity 151 member B

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Colorectal cancer, organism-specific biosystem (from KEGG)
      Colorectal cancer, organism-specific biosystemColorectal cancer (CRC) is the second largest cause of cancer-related deaths in Western countries. CRC arises from the colorectal epithelium as a result of the accumulation of genetic alterations in ...
    • Colorectal cancer, conserved biosystem (from KEGG)
      Colorectal cancer, conserved biosystemColorectal cancer (CRC) is the second largest cause of cancer-related deaths in Western countries. CRC arises from the colorectal epithelium as a result of the accumulation of genetic alterations in ...
    • Mismatch repair, organism-specific biosystem (from KEGG)
      Mismatch repair, organism-specific biosystemDNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preven...
    • Mismatch repair, conserved biosystem (from KEGG)
      Mismatch repair, conserved biosystemDNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preven...
    • Pathways in cancer, organism-specific biosystem (from KEGG)
      Pathways in cancer, organism-specific biosystem
      Pathways in cancer
    • Platinum drug resistance, organism-specific biosystem (from KEGG)
      Platinum drug resistance, organism-specific biosystemPlatinum-based drugs cisplatin, carboplatin and oxaliplatin are widely used in the therapy of solid malignancies, including testicular, ovarian, head and neck, colorectal, bladder and lung cancers. T...
    • Platinum drug resistance, conserved biosystem (from KEGG)
      Platinum drug resistance, conserved biosystemPlatinum-based drugs cisplatin, carboplatin and oxaliplatin are widely used in the therapy of solid malignancies, including testicular, ovarian, head and neck, colorectal, bladder and lung cancers. T...

    General protein information

    Preferred Names
    DNA mismatch repair protein Msh3

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009157.3 Reference EquCab3.0 Primary Assembly

      Range
      85447176..85602857 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001503855.4XP_001503905.2  DNA mismatch repair protein Msh3

      Conserved Domains (1) summary
      COG0249
      Location:2221103
      MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
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