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    ARRB2 arrestin beta 2 [ Equus caballus (horse) ]

    Gene ID: 100072892, updated on 14-Jan-2019

    Summary

    Official Symbol
    ARRB2provided by VGNC
    Official Full Name
    arrestin beta 2provided by VGNC
    Primary source
    VGNC:VGNC:15544
    See related
    Ensembl:ENSECAG00000018471
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs

    Genomic context

    See ARRB2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 11 NC_009154.3 (50099711..50108747, complement)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 11 NC_009154.2 (49759538..49766449, complement)

    Chromosome 11 - NC_009154.3Genomic Context describing neighboring genes Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene mediator complex subunit 11 Neighboring gene proline, glutamate and leucine rich protein 1 Neighboring gene arachidonate 15-lipoxygenase Neighboring gene small nucleolar RNA SNORA48

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Chemokine signaling pathway, organism-specific biosystem (from KEGG)
      Chemokine signaling pathway, organism-specific biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
    • Chemokine signaling pathway, conserved biosystem (from KEGG)
      Chemokine signaling pathway, conserved biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
    • Endocytosis, organism-specific biosystem (from KEGG)
      Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Endocytosis, conserved biosystem (from KEGG)
      Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Hedgehog signaling pathway, organism-specific biosystem (from KEGG)
      Hedgehog signaling pathway, organism-specific biosystemThe Hedgehog (Hh) signaling pathway has numerous roles in the control of cell proliferation, tissue patterning, stem cell maintenance and development. The primary cilium is an important center for tr...
    • Hedgehog signaling pathway, conserved biosystem (from KEGG)
      Hedgehog signaling pathway, conserved biosystemThe Hedgehog (Hh) signaling pathway has numerous roles in the control of cell proliferation, tissue patterning, stem cell maintenance and development. The primary cilium is an important center for tr...
    • MAPK signaling pathway, organism-specific biosystem (from KEGG)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, conserved biosystem (from KEGG)
      MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • Morphine addiction, organism-specific biosystem (from KEGG)
      Morphine addiction, organism-specific biosystemMorphine is an alkaloid from the plant extracts of opium poppy. Although morphine is highly effective for the treatment of pain, it is also known to be intensely addictive. We now know that the most ...
    • Morphine addiction, conserved biosystem (from KEGG)
      Morphine addiction, conserved biosystemMorphine is an alkaloid from the plant extracts of opium poppy. Although morphine is highly effective for the treatment of pain, it is also known to be intensely addictive. We now know that the most ...
    • Olfactory transduction, organism-specific biosystem (from KEGG)
      Olfactory transduction, organism-specific biosystemWithin the compact cilia of the olfactory receptor neurons (ORNs) a cascade of enzymatic activity transduces the binding of an odorant molecule to a receptor into an electrical signal that can be tra...
    • Olfactory transduction, conserved biosystem (from KEGG)
      Olfactory transduction, conserved biosystemWithin the compact cilia of the olfactory receptor neurons (ORNs) a cascade of enzymatic activity transduces the binding of an odorant molecule to a receptor into an electrical signal that can be tra...

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009154.3 Reference EquCab3.0 Primary Assembly

      Range
      50099711..50108747 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023653378.1XP_023509146.1  beta-arrestin-2 isoform X2

      Related
      ENSECAP00000045726.1, ENSECAT00000034901.1
      Conserved Domains (2) summary
      smart01017
      Location:194349
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19175
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    2. XM_023653377.1XP_023509145.1  beta-arrestin-2 isoform X1

      Conserved Domains (2) summary
      smart01017
      Location:209364
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:34190
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    3. XM_023653380.1XP_023509148.1  beta-arrestin-2 isoform X3

      Conserved Domains (1) summary
      smart01017
      Location:2157
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
    4. XM_023653379.1XP_023509147.1  beta-arrestin-2 isoform X3

      Conserved Domains (1) summary
      smart01017
      Location:2157
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
    5. XM_023653381.1XP_023509149.1  beta-arrestin-2 isoform X3

      Conserved Domains (1) summary
      smart01017
      Location:2157
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
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