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    SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 [ Equus caballus (horse) ]

    Gene ID: 100050923, updated on 14-Jan-2019

    Summary

    Gene symbol
    SRGAP2
    Gene description
    SLIT-ROBO Rho GTPase activating protein 2
    See related
    Ensembl:ENSECAG00000014082
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs

    Genomic context

    See SRGAP2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 5 NC_009148.3 (2504399..2740257)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 5 NC_009148.2 (2534558..2732918)

    Chromosome 5 - NC_009148.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106783141 Neighboring gene family with sequence similarity 72 member A Neighboring gene inhibitor of nuclear factor kappa B kinase subunit epsilon Neighboring gene Ras association domain family member 5

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Axon guidance, organism-specific biosystem (from KEGG)
      Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
    • Axon guidance, conserved biosystem (from KEGG)
      Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    SLIT-ROBO Rho GTPase-activating protein 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009148.3 Reference EquCab3.0 Primary Assembly

      Range
      2504399..2740257
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023640433.1XP_023496201.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X1

      Conserved Domains (4) summary
      cd07682
      Location:26289
      F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
      cd11955
      Location:756808
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:487698
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl28111
      Location:10001102
      Marek_A; Marek's disease glycoprotein A
    2. XM_023640435.1XP_023496203.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X3

      Conserved Domains (4) summary
      cd07682
      Location:26289
      F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
      cd11955
      Location:756808
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:487698
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl28111
      Location:9871089
      Marek_A; Marek's disease glycoprotein A
    3. XM_023640436.1XP_023496204.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X4

      Conserved Domains (4) summary
      cd07682
      Location:26289
      F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
      cd11955
      Location:732784
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:487674
      RhoGAP_srGAP; RhoGAP_srGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs ...
      cl28111
      Location:9761078
      Marek_A; Marek's disease glycoprotein A
    4. XM_023640439.1XP_023496207.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X7

      Related
      ENSECAP00000026151.1, ENSECAT00000053357.1
      Conserved Domains (4) summary
      cd07682
      Location:26289
      F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
      cd11955
      Location:732784
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:487674
      RhoGAP_srGAP; RhoGAP_srGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs ...
      cl28111
      Location:9631065
      Marek_A; Marek's disease glycoprotein A
    5. XM_023640434.1XP_023496202.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X2

      Conserved Domains (4) summary
      cd07682
      Location:26288
      F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
      cd11955
      Location:755807
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:486697
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl28111
      Location:9991101
      Marek_A; Marek's disease glycoprotein A
    6. XM_023640437.1XP_023496205.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X5

      Conserved Domains (4) summary
      cd07682
      Location:26288
      F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
      cd11955
      Location:731783
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:486673
      RhoGAP_srGAP; RhoGAP_srGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs ...
      cl28111
      Location:9751077
      Marek_A; Marek's disease glycoprotein A
    7. XM_023640440.1XP_023496208.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X8

      Related
      ENSECAP00000024068.1, ENSECAT00000061621.1
      Conserved Domains (4) summary
      cd07682
      Location:26288
      F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
      cd11955
      Location:731783
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:486673
      RhoGAP_srGAP; RhoGAP_srGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs ...
      cl28111
      Location:9621064
      Marek_A; Marek's disease glycoprotein A
    8. XM_023640442.1XP_023496210.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X10

      Related
      ENSECAP00000025030.1, ENSECAT00000038942.1
      Conserved Domains (3) summary
      cd11955
      Location:756808
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:487698
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:26289
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    9. XM_023640438.1XP_023496206.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X6

      Conserved Domains (4) summary
      cd11955
      Location:725777
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:456667
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:1258
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl28111
      Location:9691071
      Marek_A; Marek's disease glycoprotein A
    10. XM_023640441.1XP_023496209.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X9

      Conserved Domains (4) summary
      cd11955
      Location:700752
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:431642
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:32233
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl28111
      Location:9441046
      Marek_A; Marek's disease glycoprotein A
    11. XM_023640443.1XP_023496211.1  SLIT-ROBO Rho GTPase-activating protein 2 isoform X11

      Conserved Domains (4) summary
      cd11955
      Location:603655
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:334545
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:1136
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl28111
      Location:847949
      Marek_A; Marek's disease glycoprotein A

    RNA

    1. XR_002807806.1 RNA Sequence

      Related
      ENSECAT00000057679.1
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