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    prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit [ Danio rerio (zebrafish) ]

    Gene ID: 100001198, updated on 14-Feb-2019

    Summary

    Official Symbol
    prkaa1provided by ZNC
    Official Full Name
    protein kinase, AMP-activated, alpha 1 catalytic subunitprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030325-1
    See related
    Ensembl:ENSDARG00000060596
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    cb116; sb:cb130; im:7154392; wu:fa94c10
    Orthologs

    Genomic context

    See prkaa1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (33240541..33255759, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (32640388..32655606, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 5 NC_007116.5 (34858439..34873657, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100001344 Neighboring gene KN motif and ankyrin repeat domains 1b Neighboring gene interferon induced transmembrane protein 1 Neighboring gene kynurenine aminotransferase 1

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    AMP-activated protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cellular response to glucose starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of TOR signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of hh target transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleotide-activated protein kinase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    5'-AMP-activated protein kinase catalytic subunit alpha-1
    Names
    ampka1
    NP_001103756.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110286.1NP_001103756.1  5'-AMP-activated protein kinase catalytic subunit alpha-1

      See identical proteins and their annotated locations for NP_001103756.1

      Status: PROVISIONAL

      Source sequence(s)
      CR382323
      UniProtKB/TrEMBL
      A5WUM0
      Related
      ENSDARP00000079966.5, ENSDART00000085531.6
      Conserved Domains (4) summary
      cd12199
      Location:398571
      AMPKA1_C; C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha 1 catalytic subunit
      smart00220
      Location:17269
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14403
      Location:286350
      UBA_AID_AAPK1; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPKalpha-1)
      cd14079
      Location:14269
      STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      33240541..33255759 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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