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    ADA adenosine deaminase [ Bos taurus (cattle) ]

    Gene ID: 280712, updated on 14-Jan-2019

    Summary

    Official Symbol
    ADAprovided by VGNC
    Official Full Name
    adenosine deaminaseprovided by VGNC
    Primary source
    VGNC:VGNC:25600
    See related
    BGD:BT12388; Ensembl:ENSBTAG00000005280
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See ADA in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 13 NC_037340.1 (73028616..73052220, complement)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 13 AC_000170.1 (73750479..73773897, complement)

    Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene cAMP-dependent protein kinase inhibitor gamma Neighboring gene small nucleolar RNA U2-30 Neighboring gene small nucleolar RNA U2-19 Neighboring gene uncharacterized LOC101902669 Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    adenosine deaminase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    adenosine catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    inosine biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleotide metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    purine ribonucleoside monophosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic vesicle lumen IEA
    Inferred from Electronic Annotation
    more info
     
    lysosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    adenosine deaminase
    Names
    adenosine aminohydrolase
    NP_776312.1
    XP_024856023.1
    XP_024856024.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173887.2NP_776312.1  adenosine deaminase

      See identical proteins and their annotated locations for NP_776312.1

      Status: PROVISIONAL

      Source sequence(s)
      AF280603
      UniProtKB/Swiss-Prot
      P56658
      Related
      ENSBTAP00000006947.4, ENSBTAT00000006947.5
      Conserved Domains (1) summary
      TIGR01430
      Location:9347
      aden_deam; adenosine deaminase

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037340.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      73028616..73052220 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025000255.1XP_024856023.1  adenosine deaminase isoform X1

      Conserved Domains (1) summary
      cl00281
      Location:9368
      metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...
    2. XM_025000256.1XP_024856024.1  adenosine deaminase isoform X2

      Conserved Domains (1) summary
      cl00281
      Location:9325
      metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...
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