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RIBA3 monofunctional riboflavin biosynthesis protein RIBA 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836096, updated on 16-Oct-2021

Summary

Gene symbol
RIBA3
Gene description
monofunctional riboflavin biosynthesis protein RIBA 3
Primary source
Araport:AT5G59750
Locus tag
AT5G59750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtRIBA3; homolog of ribA 3; MTH12.13; MTH12_13
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Genomic context

See RIBA3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
5
Sequence:
Chromosome: 5; NC_003076.8 (24073195..24075552)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene exocyst subunit exo70 family protein H7 Neighboring gene UDP-N-acetylglucosamine (UAA) transporter family Neighboring gene hypothetical protein (DUF1635) Neighboring gene Protein-tyrosine phosphatase-like, PTPLA Neighboring gene myb domain protein 59

Pathways from PubChem

General gene information

NM_001203642.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 3,4-dihydroxy-2-butanone-4-phosphate synthase activity IEA
Inferred from Electronic Annotation
more info
 
enables GTP cyclohydrolase II activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in riboflavin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
monofunctional riboflavin biosynthesis protein RIBA 3
NP_001190571.1
  • DHBP synthase RibB-like alpha/beta domain;GTP cyclohydrolase II; FUNCTIONS IN: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity, GTP cyclohydrolase II activity; INVOLVED IN: riboflavin biosynthetic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP cyclohydrolase II (InterPro:IPR000926), DHBP synthase RibB (InterPro:IPR000422), DHBP synthase RibB-like alpha/beta domain (InterPro:IPR017945); BEST Arabidopsis thaliana protein match is: GTP cyclohydrolase II (TAIR:AT5G64300.1).
NP_568913.1
  • DHBP synthase RibB-like alpha/beta domain;GTP cyclohydrolase II; FUNCTIONS IN: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity, GTP cyclohydrolase II activity; INVOLVED IN: riboflavin biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP cyclohydrolase II (InterPro:IPR000926), DHBP synthase RibB (InterPro:IPR000422), DHBP synthase RibB-like alpha/beta domain (InterPro:IPR017945); BEST Arabidopsis thaliana protein match is: GTP cyclohydrolase II (TAIR:AT5G64300.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    24073195..24075552
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001345369.1NP_001332607.1  monofunctional riboflavin biosynthesis protein RIBA 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BHH7
    Conserved Domains (1) summary
    PLN02831
    Location:67441
    PLN02831; Bifunctional GTP cyclohydrolase II/ 3,4-dihydroxy-2-butanone-4-phosphate synthase
  2. NM_125367.6NP_568913.1  monofunctional riboflavin biosynthesis protein RIBA 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568913.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FN89
    Conserved Domains (1) summary
    PLN02831
    Location:67509
    PLN02831; Bifunctional GTP cyclohydrolase II/ 3,4-dihydroxy-2-butanone-4-phosphate synthase
  3. NM_001203642.1NP_001190571.1  monofunctional riboflavin biosynthesis protein RIBA 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190571.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4KJA1
    Conserved Domains (3) summary
    PLN02831
    Location:67543
    PLN02831; Bifunctional GTP cyclohydrolase II/ 3,4-dihydroxy-2-butanone-4-phosphate synthase
    cd00641
    Location:340532
    GTP_cyclohydro2; GTP cyclohydrolase II (RibA). GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the ...
    pfam00926
    Location:104333
    DHBP_synthase; 3,4-dihydroxy-2-butanone 4-phosphate synthase
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