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GUN4 protein GENOMES UNCOUPLED 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825109, updated on 19-Aug-2022

Summary

Gene symbol
GUN4
Gene description
protein GENOMES UNCOUPLED 4
Primary source
Araport:AT3G59400
Locus tag
AT3G59400
Gene type
protein coding
RNA name
protein GENOMES UNCOUPLED 4
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
GENOMES UNCOUPLED 4
Summary
GUN, genomes uncoupled, is necessary for coupling the expression of some nuclear genes to the functional state of the chloroplast. Binds to the magnesium chelatase complex and promotes formation of the substrate,a tetrapyrrole signaling molecule. Porphyrin-binding protein that enhances the activity of Mg-chelatase. Although required for chlorophyll accumulation under normal growth conditions, GUN4 is not essential for chlorophyll synthesis.
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Genomic context

See GUN4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
1
Sequence:
Chromosome: 3; NC_003074.8 (21948501..21949796, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene farnesyltransferase A Neighboring gene glycosyltransferase family protein Neighboring gene protein kinase family protein Neighboring gene tRNA-Thr Neighboring gene crinkly4

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
protein GENOMES UNCOUPLED 4
NP_191499.1
  • GENOMES UNCOUPLED 4 (GUN4); FUNCTIONS IN: tetrapyrrole binding, enzyme binding; INVOLVED IN: chlorophyll biosynthetic process, chloroplast-nucleus signaling pathway, positive regulation of catalytic activity; LOCATED IN: chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GUN4-like (InterPro:IPR008629); Has 685 Blast hits to 680 proteins in 101 species: Archae - 0; Bacteria - 474; Metazoa - 4; Fungi - 2; Plants - 53; Viruses - 0; Other Eukaryotes - 152 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    21948501..21949796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115802.4NP_191499.1  protein GENOMES UNCOUPLED 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191499.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VZR4, Q9LX31
    UniProtKB/TrEMBL
    A0A178VB84, A0A5S9XNZ0
    Conserved Domains (1) summary
    pfam05419
    Location:81223
    GUN4; GUN4-like