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AGL16 AGAMOUS-like 16 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824890, updated on 30-Jul-2025
Official Symbol
AGL16
Official Full Name
AGAMOUS-like 16
Primary source
TAIR:AT3G57230
Locus tag
AT3G57230
See related
Araport:AT3G57230
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AGAMOUS-like 16
Summary
MADS-box transcription factor. Expressed in leaf, root and stem, with higher RNA accumulation in guard cells and trichomes.
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See AGL16 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
8
Sequence:
Chromosome: 3; NC_003074.8 (21177282..21181026)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Glycosyl transferase family 4 protein Neighboring gene beta-1,3-glucanase 3 Neighboring gene ncRNA

Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. BRASSINOSTEROID-INSENSITIVE 2 regulates salt stress tolerance in Arabidopsis by promoting AGL16 activity. Zhu T, et al. Biochem Biophys Res Commun, 2023 Oct 20. PMID 37611348
  2. Arabidopsis AGAMOUS-LIKE16 and SUPPRESSOR OF CONSTANS1 regulate the genome-wide expression and flowering time. Dong X, et al. Plant Physiol, 2023 May 2. PMID 36721922, Free PMC Article
  3. miR824-Regulated AGAMOUS-LIKE16 Contributes to Flowering Time Repression in Arabidopsis. Hu JY, et al. Plant Cell, 2014 May. PMID 24876250, Free PMC Article
  4. MicroRNA-mediated regulation of stomatal development in Arabidopsis. Kutter C, et al. Plant Cell, 2007 Aug. PMID 17704216, Free PMC Article
  5. Comprehensive interaction map of the Arabidopsis MADS Box transcription factors. de Folter S, et al. Plant Cell, 2005 May. PMID 15805477, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BRASSINOSTEROID-INSENSITIVE 2 regulates salt stress tolerance in Arabidopsis by promoting AGL16 activity.
    Title: BRASSINOSTEROID-INSENSITIVE 2 regulates salt stress tolerance in Arabidopsis by promoting AGL16 activity.
  2. Arabidopsis AGAMOUS-LIKE16 and SUPPRESSOR OF CONSTANS1 regulate the genome-wide expression and flowering time.
    Title: Arabidopsis AGAMOUS-LIKE16 and SUPPRESSOR OF CONSTANS1 regulate the genome-wide expression and flowering time.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

NM_001339845.1
NM_001339846.1
NM_001339847.1
NM_001339848.1
NM_115583.6

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables MADS box domain binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription factor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within long-day photoperiodism, flowering IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of long-day photoperiodism, flowering IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within stomatal lineage progression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  
Preferred Names
AGAMOUS-like 16
NP_001319775.1
  • AGAMOUS-like 16 (AGL16); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent, stomatal lineage progression; LOCATED IN: nucleus; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100), Transcription factor, K-box (InterPro:IPR002487); BEST Arabidopsis thaliana protein match is: AGAMOUS-like 21 (TAIR:AT4G37940.1); Has 7191 Blast hits to 7190 proteins in 917 species: Archae - 0; Bacteria - 14; Metazoa - 643; Fungi - 316; Plants - 6129; Viruses - 0; Other Eukaryotes - 89 (source: NCBI BLink).
NP_191282.2
  • AGAMOUS-like 16 (AGL16); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent, stomatal lineage progression; LOCATED IN: nucleus; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100), Transcription factor, K-box (InterPro:IPR002487); BEST Arabidopsis thaliana protein match is: AGAMOUS-like 21 (TAIR:AT4G37940.1); Has 7328 Blast hits to 7327 proteins in 923 species: Archae - 0; Bacteria - 10; Metazoa - 652; Fungi - 320; Plants - 6229; Viruses - 0; Other Eukaryotes - 117 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    21177282..21181026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001339845.1 → NP_001319775.1  AGAMOUS-like 16 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A2RVQ5

  2. NM_115583.6 → NP_191282.2  AGAMOUS-like 16 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191282.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A2RVQ5, Q7XYY8, Q9FPP0, Q9M2M4
    UniProtKB/TrEMBL
    A0A178VIZ5, A0A5S9XMC6
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam01486
    Location:81 → 170
    K-box; K-box region

  3. NM_001339846.1 → NP_001326285.1  AGAMOUS-like 16 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LNT5
    Conserved Domains (1) summary
    pfam01486
    Location:47 → 136
    K-box; K-box region

  4. NM_001339847.1 → NP_001326287.1  AGAMOUS-like 16 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A2RVQ5, Q7XYY8, Q9FPP0, Q9M2M4
    UniProtKB/TrEMBL
    A0A178VIZ5, A0A5S9XMC6
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam01486
    Location:81 → 170
    K-box; K-box region

  5. NM_001339848.1 → NP_001326286.1  AGAMOUS-like 16 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LNT5
    Conserved Domains (1) summary
    pfam01486
    Location:47 → 136
    K-box; K-box region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2RVQ5.1

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