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ABCC5 multidrug resistance-associated protein 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839277, updated on 10-Oct-2019

Summary

Gene symbol
ABCC5
Gene description
multidrug resistance-associated protein 5
Primary source
Araport:AT1G04120
Locus tag
AT1G04120
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA ATP BINDING CASSETTE TRANSPORTER C5; Arabidopsis thaliana ATP-binding cassette C5; ATABCC5; ATMRP5; ATP BINDING CASSETTE TRANSPORTER C5; ATP-binding cassette C5; MULTIDRUG RESISTANCE PROTEIN 5; multidrug resistance-associated protein 5
Summary
encodes a high-affinity inositol hexakisphosphate transporter that plays a role in guard cell signaling and phytate storage. It is a member of MRP subfamily / ABC transporter subfamily C.

Genomic context

See ABCC5 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
12
Sequence:
Chromosome: 1; NC_003070.9 (1064264..1071080, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene indoleacetic acid-induced protein 10 Neighboring gene Subtilase family protein Neighboring gene ncRNA Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene Transducin family protein / WD-40 repeat family protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

NM_001197977.1
NM_001331463.1
NM_100293.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity IEA
Inferred from Electronic Annotation
more info
 
ATPase activity, coupled to transmembrane movement of substances ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
sulfonylurea receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
xenobiotic transmembrane transporting ATPase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
abscisic acid-activated signaling pathway involved in stomatal movement IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular potassium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to salt stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
stomatal opening IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
chloroplast ISM
Inferred from Sequence Model
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plant-type vacuole IDA
Inferred from Direct Assay
more info
PubMed 
vacuolar membrane IDA
Inferred from Direct Assay
more info
PubMed 
vacuole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
multidrug resistance-associated protein 5
NP_001184906.1
  • multidrug resistance-associated protein 5 (MRP5); CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 3 (TAIR:AT3G13080.1).
NP_171908.1
  • multidrug resistance-associated protein 5 (MRP5); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances, sulfonylurea receptor activity; INVOLVED IN: response to salt stress, cellular potassium ion homeostasis; LOCATED IN: vacuolar membrane, plasma membrane, plant-type vacuole; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 3 (TAIR:AT3G13080.1); Has 705301 Blast hits to 367091 proteins in 4105 species: Archae - 12555; Bacteria - 572920; Metazoa - 12444; Fungi - 7893; Plants - 6883; Viruses - 23; Other Eukaryotes - 92583 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    1064264..1071080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100293.3NP_171908.1  multidrug resistance-associated protein 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_171908.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7GB25
    UniProtKB/TrEMBL
    A0A178WGC2
    Conserved Domains (4) summary
    cd03244
    Location:12661486
    ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
    cd03250
    Location:622822
    ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
    TIGR01271
    Location:2281494
    CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
    cl00549
    Location:9511195
    ABC_membrane; ABC transporter transmembrane region
  2. NM_001197977.1NP_001184906.1  multidrug resistance-associated protein 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001184906.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4I454
    Conserved Domains (4) summary
    cd03244
    Location:12661481
    ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
    cd03250
    Location:622822
    ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
    TIGR01271
    Location:2281489
    CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
    cl00549
    Location:9511195
    ABC_membrane; ABC transporter transmembrane region
  3. NM_001331463.1NP_001322077.1  multidrug resistance-associated protein 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AT08
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