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    Src SRC proto-oncogene, non-receptor tyrosine kinase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 83805, updated on 7-Apr-2019

    Summary

    Official Symbol
    Srcprovided by RGD
    Official Full Name
    SRC proto-oncogene, non-receptor tyrosine kinaseprovided by RGD
    Primary source
    RGD:620795
    See related
    Ensembl:ENSRNOG00000009495
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    mediates growth effects of both the precursor and fully processed forms of gastrins on rat intestinal epithelial cells [RGD, Feb 2006]
    Expression
    Biased expression in Brain (RPKM 86.6), Lung (RPKM 78.5) and 9 other tissues See more
    Orthologs

    Genomic context

    See Src in Genome Data Viewer
    Location:
    3q42
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (153547807..153595643)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 3 NC_005102.3 (158123674..158171912, complement)

    Chromosome 3 - NC_005102.4Genomic Context describing neighboring genes Neighboring gene mannosidase beta like Neighboring gene uncharacterized LOC108350508 Neighboring gene uncharacterized LOC102552922 Neighboring gene uncharacterized LOC102550519 Neighboring gene band 4.1-like protein 1-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    SH2 domain binding IEA
    Inferred from Electronic Annotation
    more info
     
    SH2 domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    cell adhesion molecule binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    connexin binding IEA
    Inferred from Electronic Annotation
    more info
     
    connexin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    ephrin receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    ephrin receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    estrogen receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    growth factor receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    growth factor receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    heme binding ISO
    Inferred from Sequence Orthology
    more info
     
    heme binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    insulin receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ion channel binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ion channel binding ISO
    Inferred from Sequence Orthology
    more info
     
    kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    kinase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    non-membrane spanning protein tyrosine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphoprotein binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphoprotein binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein C-terminus binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein C-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase C binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein tyrosine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein tyrosine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein tyrosine kinase activity TAS
    Traceable Author Statement
    more info
     
    protein-containing complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    scaffold protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    scaffold protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin protein ligase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    activation of protein kinase B activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    adherens junction organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    angiotensin-activated signaling pathway involved in heart process IEA
    Inferred from Electronic Annotation
    more info
     
    angiotensin-activated signaling pathway involved in heart process ISO
    Inferred from Sequence Orthology
    more info
     
    bone resorption IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    bone resorption ISO
    Inferred from Sequence Orthology
    more info
     
    bone resorption ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    branching involved in mammary gland duct morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    branching involved in mammary gland duct morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell-cell adhesion IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to fatty acid IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to fluid shear stress IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to fluid shear stress ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to hydrogen peroxide IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to hydrogen peroxide ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to hypoxia IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to insulin stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to lipopolysaccharide IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to peptide hormone stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to platelet-derived growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to platelet-derived growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to progesterone stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to reactive oxygen species ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to transforming growth factor beta stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    epidermal growth factor receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    epidermal growth factor receptor signaling pathway IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    forebrain development IEA
    Inferred from Electronic Annotation
    more info
     
    forebrain development ISO
    Inferred from Sequence Orthology
    more info
     
    integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    integrin-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of anoikis IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of anoikis ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of extrinsic apoptotic signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of extrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of focal adhesion assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of intrinsic apoptotic signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of intrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of mitochondrial depolarization IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of mitochondrial depolarization ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of protein homooligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of telomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of telomerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of telomere maintenance via telomerase IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of telomere maintenance via telomerase ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neurotrophin TRK receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    odontogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    odontogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    oogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    oogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    osteoclast development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    osteoclast development ISO
    Inferred from Sequence Orthology
    more info
     
    peptidyl-serine phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    peptidyl-tyrosine autophosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peptidyl-tyrosine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of DNA biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of ERK1 and ERK2 cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of ERK1 and ERK2 cascade ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of MAP kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cyclin-dependent protein serine/threonine kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cytokine secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of epithelial cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of epithelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of glucose metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of insulin receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of intracellular signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of lamellipodium morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of lamellipodium morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of outer hair cell apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of ovarian follicle development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of peptidyl-tyrosine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of peptidyl-tyrosine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of phosphatidylinositol 3-kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of platelet-derived growth factor receptor signaling pathway IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    positive regulation of platelet-derived growth factor receptor-beta signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of platelet-derived growth factor receptor-beta signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of podosome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of podosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein autophosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of protein kinase B signaling IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of protein kinase B signaling ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein localization to nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of protein localization to nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein processing IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of protein processing ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of small GTPase mediated signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of smooth muscle cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    primary ovarian follicle growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    progesterone receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    progesterone receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    protein destabilization IEA
    Inferred from Electronic Annotation
    more info
     
    protein destabilization ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of caveolin-mediated endocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of caveolin-mediated endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell projection assembly IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cell projection assembly ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of early endosome to late endosome transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of early endosome to late endosome transport ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of epithelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of intracellular estrogen receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of intracellular estrogen receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of postsynaptic neurotransmitter receptor activity EXP
    Inferred from Experiment
    more info
    PubMed 
    regulation of postsynaptic neurotransmitter receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    response to acidic pH IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to drug IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to electrical stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to fatty acid IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to hydrogen peroxide IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to interleukin-1 IEA
    Inferred from Electronic Annotation
    more info
     
    response to interleukin-1 ISO
    Inferred from Sequence Orthology
    more info
     
    response to mechanical stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to mineralocorticoid IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to nutrient levels IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to virus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    stress fiber assembly IEA
    Inferred from Electronic Annotation
    more info
     
    stress fiber assembly ISO
    Inferred from Sequence Orthology
    more info
     
    substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
     
    substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
     
    transcytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    transforming growth factor beta receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    transmembrane receptor protein tyrosine kinase signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    uterus development IEA
    Inferred from Electronic Annotation
    more info
     
    uterus development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    actin filament IEA
    Inferred from Electronic Annotation
    more info
     
    actin filament ISO
    Inferred from Sequence Orthology
    more info
     
    caveola IDA
    Inferred from Direct Assay
    more info
    PubMed 
    caveola ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol NAS
    Non-traceable Author Statement
    more info
    PubMed 
    cytosol TAS
    Traceable Author Statement
    more info
     
    extrinsic component of cytoplasmic side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    glutamatergic synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    late endosome IEA
    Inferred from Electronic Annotation
    more info
     
    late endosome ISO
    Inferred from Sequence Orthology
    more info
     
    lysosome IEA
    Inferred from Electronic Annotation
    more info
     
    lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane TAS
    Traceable Author Statement
    more info
     
    podosome IEA
    Inferred from Electronic Annotation
    more info
     
    podosome ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    postsynaptic specialization, intracellular component IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ruffle membrane IEA
    Inferred from Electronic Annotation
    more info
     
    ruffle membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    proto-oncogene tyrosine-protein kinase Src
    Names
    Rous sarcoma oncogene
    c-Src
    p60-Src
    pp60c-src
    proto-oncogene c-Src
    tyrosine protein kinase c-src
    tyrosine protein kinase pp60-c-src
    v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
    v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
    NP_114183.1
    XP_008760609.1
    XP_008760610.1
    XP_017447554.1
    XP_017447555.1
    XP_017447556.1
    XP_017447557.1
    XP_017447558.1
    XP_017447559.1
    XP_017447560.1
    XP_017447561.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031977.1NP_114183.1  proto-oncogene tyrosine-protein kinase Src

      See identical proteins and their annotated locations for NP_114183.1

      Status: PROVISIONAL

      Source sequence(s)
      AF157016
      UniProtKB/Swiss-Prot
      Q9WUD9
      Related
      ENSRNOP00000071837.1, ENSRNOT00000080516.1
      Conserved Domains (4) summary
      cd10365
      Location:153253
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88149
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:266542
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:276525
      Pkinase_Tyr; Protein tyrosine kinase

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005102.4 Reference Rnor_6.0 Primary Assembly

      Range
      153547807..153595643
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017592067.1XP_017447556.1  proto-oncogene tyrosine-protein kinase Src isoform X1

      UniProtKB/Swiss-Prot
      Q9WUD9
      Conserved Domains (4) summary
      cd10365
      Location:153253
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88149
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:266542
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:276525
      Pkinase_Tyr; Protein tyrosine kinase
    2. XM_017592066.1XP_017447555.1  proto-oncogene tyrosine-protein kinase Src isoform X1

      UniProtKB/Swiss-Prot
      Q9WUD9
      Conserved Domains (4) summary
      cd10365
      Location:153253
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88149
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:266542
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:276525
      Pkinase_Tyr; Protein tyrosine kinase
    3. XM_017592070.1XP_017447559.1  proto-oncogene tyrosine-protein kinase Src isoform X1

      UniProtKB/Swiss-Prot
      Q9WUD9
      Conserved Domains (4) summary
      cd10365
      Location:153253
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88149
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:266542
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:276525
      Pkinase_Tyr; Protein tyrosine kinase
    4. XM_017592065.1XP_017447554.1  proto-oncogene tyrosine-protein kinase Src isoform X1

      UniProtKB/Swiss-Prot
      Q9WUD9
      Conserved Domains (4) summary
      cd10365
      Location:153253
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88149
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:266542
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:276525
      Pkinase_Tyr; Protein tyrosine kinase
    5. XM_017592069.1XP_017447558.1  proto-oncogene tyrosine-protein kinase Src isoform X1

      UniProtKB/Swiss-Prot
      Q9WUD9
      Conserved Domains (4) summary
      cd10365
      Location:153253
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88149
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:266542
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:276525
      Pkinase_Tyr; Protein tyrosine kinase
    6. XM_017592068.1XP_017447557.1  proto-oncogene tyrosine-protein kinase Src isoform X1

      UniProtKB/Swiss-Prot
      Q9WUD9
      Conserved Domains (4) summary
      cd10365
      Location:153253
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88149
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:266542
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:276525
      Pkinase_Tyr; Protein tyrosine kinase
    7. XM_017592071.1XP_017447560.1  proto-oncogene tyrosine-protein kinase Src isoform X1

      UniProtKB/Swiss-Prot
      Q9WUD9
      Conserved Domains (4) summary
      cd10365
      Location:153253
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88149
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:266542
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:276525
      Pkinase_Tyr; Protein tyrosine kinase
    8. XM_008762388.2XP_008760610.1  proto-oncogene tyrosine-protein kinase Src isoform X1

      See identical proteins and their annotated locations for XP_008760610.1

      UniProtKB/Swiss-Prot
      Q9WUD9
      Conserved Domains (4) summary
      cd10365
      Location:153253
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88149
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:266542
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:276525
      Pkinase_Tyr; Protein tyrosine kinase
    9. XM_008762387.2XP_008760609.1  proto-oncogene tyrosine-protein kinase Src isoform X1

      See identical proteins and their annotated locations for XP_008760609.1

      UniProtKB/Swiss-Prot
      Q9WUD9
      Conserved Domains (4) summary
      cd10365
      Location:153253
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88149
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:266542
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:276525
      Pkinase_Tyr; Protein tyrosine kinase
    10. XM_017592072.1XP_017447561.1  proto-oncogene tyrosine-protein kinase Src isoform X2

      UniProtKB/Swiss-Prot
      Q9WUD9
      Related
      ENSRNOP00000012739.2, ENSRNOT00000012739.4
      Conserved Domains (4) summary
      cd10365
      Location:147247
      SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
      cd12008
      Location:88143
      SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
      cd05071
      Location:260536
      PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
      pfam07714
      Location:270519
      Pkinase_Tyr; Protein tyrosine kinase

    Alternate Rn_Celera

    Genomic

    1. AC_000071.1 Alternate Rn_Celera

      Range
      144830256..144843524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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