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    Dvl1 dishevelled segment polarity protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 83721, updated on 19-Apr-2019

    Summary

    Official Symbol
    Dvl1provided by RGD
    Official Full Name
    dishevelled segment polarity protein 1provided by RGD
    Primary source
    RGD:620632
    See related
    Ensembl:ENSRNOG00000019423
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    dvl-1
    Summary
    mouse homolog contributes to social and sensorimotor behavior [RGD, Feb 2006]
    Expression
    Biased expression in Muscle (RPKM 227.6), Kidney (RPKM 183.6) and 9 other tissues See more
    Orthologs

    Genomic context

    See Dvl1 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (173295948..173308014)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (176771577..176783630)

    Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene aurora kinase A interacting protein 1 Neighboring gene matrix remodeling associated 8 Neighboring gene taste 1 receptor member 3 Neighboring gene ceramide-1-phosphate transfer protein Neighboring gene integrator complex subunit 11 Neighboring gene pseudouridine synthase like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Adipogenesis, organism-specific biosystem (from WikiPathways)
      Adipogenesis, organism-specific biosystemThe different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, compo...
    • Basal cell carcinoma, organism-specific biosystem (from KEGG)
      Basal cell carcinoma, organism-specific biosystemCancer of the skin is the most common cancer in Caucasians and basal cell carcinomas (BCC) account for 90% of all skin cancers. The vast majority of BCC cases are sporadic, though there is a rare fam...
    • Basal cell carcinoma, conserved biosystem (from KEGG)
      Basal cell carcinoma, conserved biosystemCancer of the skin is the most common cancer in Caucasians and basal cell carcinomas (BCC) account for 90% of all skin cancers. The vast majority of BCC cases are sporadic, though there is a rare fam...
    • Breast cancer, organism-specific biosystem (from KEGG)
      Breast cancer, organism-specific biosystemBreast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gla...
    • Breast cancer, conserved biosystem (from KEGG)
      Breast cancer, conserved biosystemBreast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gla...
    • Degradation of DVL, organism-specific biosystem (from REACTOME)
      Degradation of DVL, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Disassembly of the destruction complex and recruitment of AXIN to the membrane, organism-specific biosystem (from REACTOME)
      Disassembly of the destruction complex and recruitment of AXIN to the membrane, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • HTLV-I infection, organism-specific biosystem (from KEGG)
      HTLV-I infection, organism-specific biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
    • HTLV-I infection, conserved biosystem (from KEGG)
      HTLV-I infection, conserved biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
    • Hippo signaling pathway, organism-specific biosystem (from KEGG)
      Hippo signaling pathway, organism-specific biosystemHippo signaling is an evolutionarily conserved signaling pathway that controls organ size from flies to humans. In humans and mice, the pathway consists of the MST1 and MST2 kinases, their cofactor S...
    • Hippo signaling pathway, conserved biosystem (from KEGG)
      Hippo signaling pathway, conserved biosystemHippo signaling is an evolutionarily conserved signaling pathway that controls organ size from flies to humans. In humans and mice, the pathway consists of the MST1 and MST2 kinases, their cofactor S...
    • Melanogenesis, organism-specific biosystem (from KEGG)
      Melanogenesis, organism-specific biosystemCutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory cont...
    • Melanogenesis, conserved biosystem (from KEGG)
      Melanogenesis, conserved biosystemCutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory cont...
    • Notch Signaling Pathway, organism-specific biosystem (from WikiPathways)
      Notch Signaling Pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Notch signaling pathway, organism-specific biosystem (from KEGG)
      Notch signaling pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Notch signaling pathway, conserved biosystem (from KEGG)
      Notch signaling pathway, conserved biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Pathways in cancer, organism-specific biosystem (from KEGG)
      Pathways in cancer, organism-specific biosystem
      Pathways in cancer
    • Signal Transduction, organism-specific biosystem (from REACTOME)
      Signal Transduction, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Signaling by Wnt, organism-specific biosystem (from REACTOME)
      Signaling by Wnt, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Signaling pathways regulating pluripotency of stem cells, organism-specific biosystem (from KEGG)
      Signaling pathways regulating pluripotency of stem cells, organism-specific biosystemPluripotent stem cells (PSCs) are basic cells with an indefinite self-renewal capacity and the potential to generate all the cell types of the three germinal layers. The types of PSCs known to date i...
    • Signaling pathways regulating pluripotency of stem cells, conserved biosystem (from KEGG)
      Signaling pathways regulating pluripotency of stem cells, conserved biosystemPluripotent stem cells (PSCs) are basic cells with an indefinite self-renewal capacity and the potential to generate all the cell types of the three germinal layers. The types of PSCs known to date i...
    • TCF dependent signaling in response to WNT, organism-specific biosystem (from REACTOME)
      TCF dependent signaling in response to WNT, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • WNT mediated activation of DVL, organism-specific biosystem (from REACTOME)
      WNT mediated activation of DVL, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Wnt Signaling Pathway, organism-specific biosystem (from WikiPathways)
      Wnt Signaling Pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
    • Wnt Signaling Pathway NetPath, organism-specific biosystem (from WikiPathways)
      Wnt Signaling Pathway NetPath, organism-specific biosystemWnt family of proteins are a large family of cysteine-rich secreted glycoproteins that regulate cell-cell interactions. They bind to members of the Frizzled family of 7 transmembrane receptors. Bindi...
    • Wnt Signaling Pathway and Pluripotency, organism-specific biosystem (from WikiPathways)
      Wnt Signaling Pathway and Pluripotency, organism-specific biosystemThis pathway was adapted from several resources and is designed to provide a theoretical frame-work for examining Wnt signaling and interacting components in the context of embryonic stem-cell pluri...
    • Wnt signaling, organism-specific biosystem (from KEGG)
      Wnt signaling, organism-specific biosystemFunctional set; Cellular processes; Cell signaling
    • Wnt signaling, conserved biosystem (from KEGG)
      Wnt signaling, conserved biosystemFunctional set; Cellular processes; Cell signaling
    • Wnt signaling pathway, organism-specific biosystem (from KEGG)
      Wnt signaling pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
    • Wnt signaling pathway, conserved biosystem (from KEGG)
      Wnt signaling pathway, conserved biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
    • mTOR signaling pathway, organism-specific biosystem (from KEGG)
      mTOR signaling pathway, organism-specific biosystemThe mammalian (mechanistic) target of rapamycin (mTOR) is a highly conserved serine/threonine protein kinase, which exists in two complexes termed mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 conta...
    • mTOR signaling pathway, conserved biosystem (from KEGG)
      mTOR signaling pathway, conserved biosystemThe mammalian (mechanistic) target of rapamycin (mTOR) is a highly conserved serine/threonine protein kinase, which exists in two complexes termed mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 conta...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    Rac GTPase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    beta-catenin binding IEA
    Inferred from Electronic Annotation
    more info
     
    beta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    frizzled binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    frizzled binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    Wnt signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Wnt signaling pathway TAS
    Traceable Author Statement
    more info
    PubMed 
    Wnt signaling pathway, planar cell polarity pathway ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    axon extension IEA
    Inferred from Electronic Annotation
    more info
     
    axon extension ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    axon guidance IEA
    Inferred from Electronic Annotation
    more info
     
    axon guidance ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    axonogenesis ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cochlea morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    cochlea morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    collateral sprouting IEA
    Inferred from Electronic Annotation
    more info
     
    collateral sprouting ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    convergent extension involved in neural plate elongation IEA
    Inferred from Electronic Annotation
    more info
     
    convergent extension involved in neural plate elongation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    convergent extension involved in organogenesis ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoplasmic microtubule organization IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic microtubule organization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    dendrite morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    dendritic spine morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of protein binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neural tube development ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neuromuscular junction development ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neurotransmitter secretion IEA
    Inferred from Electronic Annotation
    more info
     
    neurotransmitter secretion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    planar cell polarity pathway involved in neural tube closure IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    planar cell polarity pathway involved in neural tube closure ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of excitatory postsynaptic potential IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of neuron projection arborization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of neuron projection development ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    postsynapse organization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    prepulse inhibition IEA
    Inferred from Electronic Annotation
    more info
     
    prepulse inhibition ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    presynapse assembly IEA
    Inferred from Electronic Annotation
    more info
     
    presynapse assembly ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein localization to microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    protein localization to microtubule ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein localization to nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    protein localization to nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein stabilization IEA
    Inferred from Electronic Annotation
    more info
     
    protein stabilization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    receptor clustering ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of cellular protein localization IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cellular protein localization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of neurotransmitter levels ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of synaptic vesicle exocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of synaptic vesicle exocytosis ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    skeletal muscle acetylcholine-gated channel clustering IEA
    Inferred from Electronic Annotation
    more info
     
    skeletal muscle acetylcholine-gated channel clustering ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    social behavior IEA
    Inferred from Electronic Annotation
    more info
     
    social behavior ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    synapse organization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    Schaffer collateral - CA1 synapse IEA
    Inferred from Electronic Annotation
    more info
     
    Schaffer collateral - CA1 synapse ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Wnt signalosome IEA
    Inferred from Electronic Annotation
    more info
     
    Wnt signalosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axon ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    clathrin-coated vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    clathrin-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    colocalizes_with cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    colocalizes_with cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dendritic spine IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    growth cone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    growth cone ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    lateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    lateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    colocalizes_with microtubule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    presynapse IEA
    Inferred from Electronic Annotation
    more info
     
    presynapse ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    synapse ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    segment polarity protein dishevelled homolog DVL-1
    Names
    DSH homolog 1
    dishevelled, dsh homolog 1
    dishevelled-1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031820.1NP_114008.1  segment polarity protein dishevelled homolog DVL-1

      See identical proteins and their annotated locations for NP_114008.1

      Status: PROVISIONAL

      Source sequence(s)
      AF143546
      UniProtKB/Swiss-Prot
      Q9WVB9
      Related
      ENSRNOP00000026439.5, ENSRNOT00000026439.5
      Conserved Domains (5) summary
      smart00021
      Location:185
      DAX; Domain present in Dishevelled and axin
      cd04438
      Location:417499
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam00595
      Location:251336
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam02377
      Location:90247
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:503685
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

      Range
      173295948..173308014
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017593659.1XP_017449148.1  segment polarity protein dishevelled homolog DVL-1 isoform X4

    2. XM_008764389.2XP_008762611.1  segment polarity protein dishevelled homolog DVL-1 isoform X2

      Conserved Domains (5) summary
      smart00021
      Location:185
      DAX; Domain present in Dishevelled and axin
      cd04438
      Location:421503
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam00595
      Location:284365
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam02377
      Location:90247
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:507689
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
    3. XM_008764390.2XP_008762612.1  segment polarity protein dishevelled homolog DVL-1 isoform X5

      Conserved Domains (4) summary
      smart00021
      Location:185
      DAX; Domain present in Dishevelled and axin
      cd04438
      Location:446528
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam00595
      Location:284365
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam02377
      Location:90247
      Dishevelled; Dishevelled specific domain
    4. XM_008764388.2XP_008762610.1  segment polarity protein dishevelled homolog DVL-1 isoform X1

      Conserved Domains (5) summary
      smart00021
      Location:185
      DAX; Domain present in Dishevelled and axin
      cd04438
      Location:446528
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam00595
      Location:284365
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam02377
      Location:90247
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:532714
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
    5. XM_006239598.3XP_006239660.1  segment polarity protein dishevelled homolog DVL-1 isoform X3

      Conserved Domains (5) summary
      smart00021
      Location:185
      DAX; Domain present in Dishevelled and axin
      cd04438
      Location:392474
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam00595
      Location:251336
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam02377
      Location:90247
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:478660
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
    6. XM_008764391.2XP_008762613.1  segment polarity protein dishevelled homolog DVL-1 isoform X6

      Conserved Domains (4) summary
      cd04438
      Location:316398
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam00595
      Location:154235
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam02377
      Location:1117
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:402584
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

    Alternate Rn_Celera

    Genomic

    1. AC_000073.1 Alternate Rn_Celera

      Range
      164657716..164669383
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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