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    ERBB3 erb-b2 receptor tyrosine kinase 3 [ Bos taurus (cattle) ]

    Gene ID: 785655, updated on 14-Jan-2019

    Summary

    Official Symbol
    ERBB3provided by VGNC
    Official Full Name
    erb-b2 receptor tyrosine kinase 3provided by VGNC
    Primary source
    VGNC:VGNC:28564
    See related
    Ensembl:ENSBTAG00000010444
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See ERBB3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 5 NC_037332.1 (57215783..57236737, complement)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 5 AC_000162.1 (57539932..57560884, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101903253 Neighboring gene zinc finger CCCH-type containing 10 Neighboring gene proliferation-associated 2G4 Neighboring gene ribosomal protein S26 Neighboring gene IKAROS family zinc finger 4

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC143211

    General protein information

    Preferred Names
    receptor tyrosine-protein kinase erbB-3
    Names
    v-erb-b2 erythroblastic leukemia viral oncogene homolog 3
    NP_001096575.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001103105.1NP_001096575.1  receptor tyrosine-protein kinase erbB-3 precursor

      See identical proteins and their annotated locations for NP_001096575.1

      Status: PROVISIONAL

      Source sequence(s)
      BC150128
      UniProtKB/TrEMBL
      A6QR62
      Related
      ENSBTAP00000013790.5, ENSBTAT00000013790.6
      Conserved Domains (8) summary
      cd05111
      Location:700978
      PTK_HER3; Pseudokinase domain of the Protein Tyrosine Kinase, HER3
      cd12095
      Location:637675
      TM_ErbB3; Transmembrane domain of ErbB3, a Protein Tyrosine Kinase
      smart00261
      Location:547589
      FU; Furin-like repeats
      cd00064
      Location:500552
      FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
      pfam00757
      Location:182329
      Furin-like; Furin-like cysteine rich region
      pfam01030
      Location:353474
      Recep_L_domain; Receptor L domain
      pfam07714
      Location:708964
      Pkinase_Tyr; Protein tyrosine kinase
      pfam14843
      Location:499629
      GF_recep_IV; Growth factor receptor domain IV

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      57215783..57236737 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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